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116464 Ncoa6

116464

Ncoa6

nuclear receptor coactivator 6

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition nuclear receptor coactivator 6

研究结论

Date Results Publications
2019-02-09 10:04:00 the processing of a subset of neuronal precursor microRNAs, among them the dendritically localized pre-miR16, was impaired. Decreased production of miR-16-5p, which targeted the BDNF mRNA itself, was rescued by expression of a membrane-targeted TRBP Moreover, miR-16-5p or membrane-targeted TRBP expression blocked BDNF-induced dendritogenesis, demonstrating the importance of neuronal TRBP dynamics 29263199
2013-05-18 10:30:00 PRIP inhibits regulated exocytosis through the interaction of its C2 domain with syntaxin 1 and SNAP-25, potentially competing with accessory proteins such as synaptotagmin I and by directly inhibiting trans-SNARE complex formation 23341457
2012-05-19 10:47:00 PRIP is involved in the regulation of the phospho-states of SNAP-25 by modulating the activity of PP1, thus regulating exocytosis. 22311984
2010-01-21 00:00:00 Primary islets ectopically expressing dominant-negative fragments of ASC-2 exhibited decreased insulin secretion. 16738321
2010-01-21 00:00:00 may play potential roles in follicular development and ovulation 12374465

名称对应

Type IDs
Synonymous Aib3, NRC, PRIP, RAP250, Trbp
Gene
UniProtKB-ID: G3V8C9_RAT
UniprotKB: G3V8C9
UniParc: UPI0000502EE4
EMBL: CH474050, AABR07072941
Ensembl: ENSRNOG00000018288
KO: rno:116464
Nucleutide sequences
EMBL-CDS: EDL85918.1
Gene_ORFName: rCG_37248
Ensembl_TRS: ENSRNOT00000024714
Protein sequencees
Ensembl_PRO: ENSRNOP00000024714
RefSeq: XP_008760518.1, XP_008760521.1, NP_001263643.1, XP_008760520.1, XP_006235358.1, XP_008760517.1, XP_008760519.1
Others
UniRef100: UniRef100_G3V8C9
UniRef90: UniRef90_A0A337SAS9
UniRef50: UniRef50_Q14686
UniGene: Rn.9077, Rn.234544

全选

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研究热度

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