| Type | Description |
|---|---|
| Definition | interleukin 22 receptor subunit alpha 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 15:59:00 | The Rare IL22RA2 Coding Variant rs28385692 Decreases Secretion of IL-22BP Isoform-1, -2 and -3 and Is Associated with Risk for Multiple Sclerosis. | 31936765 |
| 2020-04-11 12:41:00 | Our results demonstrate a pathogenic role of IL-22BP in three species with a potential mechanism of action involving T cell polarization | 31292217 |
| 2019-10-26 10:25:00 | Upon silencing of interleukin 22 receptor subunit alpha 2 (IL22RA2) expression in immature dendritic cells (moDC), molecular chaperone GRP78 (GRP78) levels were significantly reduced, suggesting that native IL22RA2 expression naturally contributes to upregulating GRP78 levels in these cells. | 30619294 |
| 2019-09-28 12:37:00 | IL-22BP expression was downregulated in skin biopsies of psoriasis patients compared to the skin of healthy donors. | 29572462 |
| 2018-09-29 11:30:00 | expression higher in the epidermal compartment of the skin in comparison with dermis in both healthy skin and psoriasis skin | 27676439 |
| Type | IDs |
|---|---|
| Synonymous | CRF2-10, CRF2-S1, CRF2X, IL-22BP, IL-22R-alpha-2, IL-22RA2, ZCYTOR16 |
| Gene |
UniProtKB-ID:
I22R2_HUMAN
UniprotKB:
Q969J5
UniParc:
UPI000003C1F4,
UPI000006F005,
UPI0000062347
EMBL:
AJ313161,
AY040568,
AY040567,
AY040566,
AY358737,
AY779023,
AL050337,
AJ313162,
BC125168,
BC125167,
AY358111,
AY044429,
AJ297262,
CH471051
Ensembl:
ENSG00000164485
KO:
hsa:116379
|
| Nucleutide sequences |
EMBL-CDS:
EAW47933.1,
AAK85715.1,
AAK85716.1,
AAV31775.1,
AAI25169.1,
AAQ89097.1,
AAK85714.1,
AAQ88478.1,
AAI25168.1,
CAC85634.1,
CAC83097.1,
AAK91775.1,
CAC85635.1
Gene_ORFName:
UNQ5793/PRO19598/PRO19822
Ensembl_TRS:
ENST00000349184,
ENST00000296980,
ENST00000339602
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000296979,
ENSP00000296980,
ENSP00000340920
RefSeq:
NP_851826.1,
NP_851827.1,
NP_443194.1
|
| Others |
UniRef100:
UniRef100_Q969J5
UniRef90:
UniRef90_Q969J5
UniRef50:
UniRef50_Q969J5
UniGene:
Hs.126891
CCDS:
CCDS5183.1,
CCDS5184.1,
CCDS5182.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员