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11611 Agxt

11611

Agxt

alanine-glyoxylate aminotransferase

protein-coding

Mus musculus

基因描述

Type Description
Definition alanine-glyoxylate aminotransferase

研究结论

Date Results Publications
2020-07-25 10:54:00 two human constructs, wild-type and engineered AGT (RHEAM), were tested in Agxt(-/-) mice. Repeat dosing in Agxt(-/-) mice resulted in a 40% reduction in urinary oxalate, suggesting therapeutic benefit. 30676254
2017-09-23 10:11:00 AGT-deficient mice showed decreased vascular permeability, a readout of in vivo histamine activity. 27239044
2010-01-21 00:00:00 expressed wild-type human AGT1 was predominantly localized in mouse hepatocellular peroxisomes, whereas the most common mutant form of AGT1 (G170R) was localized predominantly in the mitochondria 17110443

名称对应

Type IDs
Synonymous AGT, Agt1, Agxt1, SPT
Gene
UniProtKB-ID: SPYA_MOUSE, Q3UEN9_MOUSE
UniprotKB: O35423, Q3UEN9
UniParc: UPI000058AFF4, UPI00000E6DA1
EMBL: AC110247, CH466520, AF027730, AK149432, BC025799
Ensembl: ENSMUSG00000026272
KO: mmu:11611
Nucleutide sequences
EMBL-CDS: AAB82001.2, AAH25799.1, EDL39972.1, BAE28872.1
Ensembl_TRS: ENSMUST00000027491
Protein sequencees
Ensembl_PRO: ENSMUSP00000027491
RefSeq: NP_001263639.1, NP_057911.2
Others
UniRef100: UniRef100_O35423
UniRef90: UniRef90_P09139
UniRef50: UniRef50_P09139
UniGene: Mm.7457
CCDS: CCDS15184.1

全选

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