| Type | Description |
|---|---|
| Definition | ERCC excision repair 8, CSA ubiquitin ligase complex subunit |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:38:00 | Atypical features and de novo heterozygous mutations in two siblings with Cockayne syndrome. | 32160415 |
| 2021-04-03 13:34:00 | Integrative genomic analysis implicates ERCC6 and its interaction with ERCC8 in susceptibility to breast cancer. | 33277540 |
| 2020-10-03 12:53:00 | Multimodal imaging in a family with Cockayne syndrome with a novel pathogenic mutation in the ERCC8 gene, and significant phenotypic variability. | 32048102 |
| 2020-08-13 09:32:00 | TCR is initiated by RNAPIIo-bound CSB, which recruits CSA through a newly identified CSA-interaction motif (CIM); once recruited, CSA facilitates the association of UVSSA with stalled RNAPIIo; in addition, UVSSA is the key factor that recruits the TFIIH complex in a manner that is stimulated by CSB and CSA | 32355176 |
| 2020-05-23 12:47:00 | convergent and divergent roles for CSA and CSB in DNA repair and transcription regulation | 31546172 |
| Type | IDs |
|---|---|
| Synonymous | CKN1, CSA, UVSS2 |
| Gene |
UniProtKB-ID:
ERCC8_HUMAN,
B3KPW7_HUMAN,
B4DGZ9_HUMAN,
A0A0S2Z3L1_HUMAN
UniprotKB:
Q13216,
B3KPW7,
B4DGZ9,
A0A0S2Z3L1
UniParc:
UPI00017A6F48,
UPI000013D5B0,
UPI00000729FE,
UPI000000D8F8
EMBL:
AK294856,
AK056931,
U28413,
KU177979,
CR536563,
AK314511,
AY213194,
CH471123,
BT020021,
BC009793
Ensembl:
ENSG00000049167
KO:
hsa:1161
|
| Nucleutide sequences |
EMBL-CDS:
EAW55004.1,
AAO21128.1,
AAH09793.1,
BAG37111.1,
AAV38824.1,
CAG38800.1,
AAA82605.1,
BAG51829.1,
BAG57960.1,
EAW55003.1,
ALQ33437.1
Gene_ORFName:
hCG_2003063
Ensembl_TRS:
ENST00000265038
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000265038
RefSeq:
NP_000073.1,
NP_001007234.1,
NP_001007235.1,
NP_001277214.1
|
| Others |
UniRef100:
UniRef100_Q13216-2,
UniRef100_A0A2J8KKX7,
UniRef100_Q13216
UniRef90:
UniRef90_Q13216,
UniRef90_A0A1S2ZBV0,
UniRef90_Q13216-2
UniRef50:
UniRef50_A0A672KJ13,
UniRef50_Q13216-2,
UniRef50_Q13216
UniGene:
Hs.435237
CCDS:
CCDS3978.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员