| Type | Description |
|---|---|
| Definition | solute carrier family 22 member 12 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:11:00 | Uric Acid Has Direct Proinflammatory Effects on Human Macrophages by Increasing Proinflammatory Mediators and Bacterial Phagocytosis Probably via URAT1. | 32283759 |
| 2021-03-28 19:06:00 | Identification of a dysfunctional splicing mutation in the SLC22A12/URAT1 gene causing renal hypouricaemia type 1: a report on two families. | 33011794 |
| 2021-02-27 13:48:00 | Glucose, Fructose, and Urate Transporters in the Choroid Plexus Epithelium. | 33008107 |
| 2020-10-31 13:16:00 | Contribution of SLC22A12 on hypouricemia and its clinical significance for screening purposes. | 31591475 |
| 2020-07-18 11:22:00 | We found a case of Renal hypouricemia carrying mutations in SLC22A12 gene accompanied with compensatory mutations associated with hyperuricemia, representing the first report showing coexistence of the mutations with opposed potential to regulate urate concentrations. | 32375679 |
| Type | IDs |
|---|---|
| Synonymous | OAT4L, RST, URAT1 |
| Gene |
UniProtKB-ID:
S22AC_HUMAN,
B3KP53_HUMAN
UniprotKB:
Q96S37,
B3KP53
UniParc:
UPI0000040C17,
UPI000066D8F5,
UPI00001A8285,
UPI000014140D,
UPI000204AEBB
EMBL:
BC053348,
DQ514594,
AY358183,
AK055737,
AC044790,
AP001092,
AB071863,
AB050269,
DQ514596,
DQ514593,
AK315061,
DQ514595,
CH471076
Ensembl:
ENSG00000197891
KO:
hsa:116085
|
| Nucleutide sequences |
EMBL-CDS:
ABF74570.1,
ABF74572.1,
ABF74573.1,
EAW74273.1,
BAB68364.1,
AAK68156.1,
AAH53348.1,
BAB96750.1,
EAW74274.1,
AAQ88550.1,
ABF74571.1,
BAG51565.1
Gene_ORFName:
UNQ6453/PRO34004
Ensembl_TRS:
ENST00000336464,
ENST00000377567,
ENST00000377572,
ENST00000377574,
ENST00000473690
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000366795,
ENSP00000366790,
ENSP00000366797,
ENSP00000336836,
ENSP00000438437
RefSeq:
NP_653186.2,
XP_006718493.1,
XP_006718494.1,
NP_700357.1,
NP_001263255.1,
NP_001263256.1
|
| Others |
UniRef100:
UniRef100_B3KP53,
UniRef100_Q96S37
UniRef90:
UniRef90_Q96S37,
UniRef90_B3KP53
UniRef50:
UniRef50_A0A1S3W6Y8,
UniRef50_Q96S37
UniGene:
Hs.174424,
Hs.700182
CCDS:
CCDS60835.1,
CCDS60836.1,
CCDS8075.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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