| Type | Description |
|---|---|
| Definition | RecQ mediated genome instability 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-06 13:41:00 | EPHX2 and RMI2 were noted as two novel key genes for cervical squamous cell carcinoma | 31041817 |
| 2017-04-29 12:04:00 | In both patient and knockout cell lines reduced localisation of BLM to ultra fine DNA bridges and FANCD2 at foci linking bridges are observed. Overall, loss of RMI2 produces a partially active BLM complex with mild features of Bloom syndrome. | 27977684 |
| 2015-02-28 11:07:00 | The results show that Topo IIIalpha stimulates DNA unwinding by BLM in a manner that is potentiated by RMI1-RMI2, and that the processivity of resection is reliant on the Topo IIIalpha-RMI1-RMI2 complex. | 25200081 |
| 2014-02-08 10:32:00 | two proteins that interact with BLM, RMI1 and RMI2, are phosphorylated upon SAC activation, and, like BLM, RMI1, and RMI2, are phosphorylated in an MPS1-dependent manner. | 24108125 |
| 2011-01-22 11:03:00 | Crystal structures of RMI1 and RMI2, two OB-fold regulatory subunits of the BLM complex | 20826342 |
| Type | IDs |
|---|---|
| Synonymous | BLAP18, C16orf75 |
| Gene |
UniProtKB-ID:
RMI2_HUMAN
UniprotKB:
Q96E14
UniParc:
UPI000006EA0A,
UPI000056F1A0
EMBL:
CH471112,
BC039361,
AC009121,
AK123764,
BC022427,
BC031016,
BC013040
Ensembl:
ENSG00000175643
KO:
hsa:116028
|
| Nucleutide sequences |
EMBL-CDS:
AAH39361.1,
EAW85155.1,
AAH31016.1,
AAH22427.1,
AAH13040.2,
BAG53958.1
Ensembl_TRS:
ENST00000312499,
ENST00000572173
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000461206,
ENSP00000310356
RefSeq:
NP_689521.1
|
| Others |
UniRef100:
UniRef100_Q96E14
UniRef90:
UniRef90_Q96E14
UniRef50:
UniRef50_Q96E14
UniGene:
Hs.347524
CCDS:
CCDS10548.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员