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11600 Angpt1

11600

Angpt1

angiopoietin 1

protein-coding

Mus musculus

基因描述

Type Description
Definition angiopoietin 1

研究结论

Date Results Publications
2021-03-13 13:20:00 Sulfated glycans engage the Ang-Tie pathway to regulate vascular development. 33020664
2020-08-22 15:25:00 Inhibition of microRNA-711 limits angiopoietin-1 and Akt changes, tissue damage, and motor dysfunction after contusive spinal cord injury in mice. 31685802
2020-05-16 11:09:00 Study of ApoE-/- mice transfected with Ang-1 encoding lentiviral vector suggested that Ang-1 acted as promoter of atherosclerosis through reduction of macrophage cholesterol efflux via binding to Tie2. Ang-1 incubated with human THP-1 derived macrophages activated the Tie2/TFE3 pathway to reduce LXRalpha-mediated ABCA1 and ABCG1 expression and subsequent cholesterol efflux. 31678621
2020-05-09 12:48:00 published rodent data suggest that angiopoietin-1 upregulation improves outcome following temporary cerebral ischaemia by reducing cerebral infarction size and improving blood-brain barrier integrity. 31581897
2020-03-28 11:25:00 accelerates Alzheimer's disease via FOXA2/PEN2/APP pathway in APP/PS1 mice 32061671

名称对应

Type IDs
Synonymous 1110046O21Rik, Ang-1, Ang1
Gene
UniProtKB-ID: ANGP1_MOUSE
UniprotKB: O08538
UniParc: UPI0000021E83
EMBL: BC067410, U83509
Ensembl: ENSMUSG00000022309
KO: mmu:11600
Nucleutide sequences
EMBL-CDS: AAB50558.1, AAH67410.1
Ensembl_TRS: ENSMUST00000022921
Protein sequencees
Ensembl_PRO: ENSMUSP00000022921
RefSeq: NP_033770.2, XP_036014971.1, NP_001272991.1, XP_036014970.1, XP_006520386.1
Others
UniRef100: UniRef100_O08538
UniRef90: UniRef90_O08538
UniRef50: UniRef50_Q15389
UniGene: Mm.309336
CCDS: CCDS27450.1

全选

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研究热度

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