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1159 CKMT1B

1159

CKMT1B

creatine kinase, mitochondrial 1B

protein-coding

Homo sapiens

基因描述

Type Description
Definition creatine kinase, mitochondrial 1B

研究结论

Date Results Publications
2018-07-07 12:11:00 The highly conserved residue E227 acts as the catalytic base to accept the guanidinium proton transferred from creatine in UMTCK. 27909311
2017-08-12 11:52:00 Mitochondrial creatine kinase CKMT1 is necessary for survival of EVI1-expressing cells in subjects with EVI1-positive AML. 28191887
2015-01-17 10:34:00 LRRK2 can interact directly with uMtCK to block its entry into mitochondria and its subsequent processing. 21370995
2014-12-06 12:15:00 CKMT1 is a key regulator of the permeability transition pore through a complex that is distinct from the classical permeability transition pore. 24522192
2014-04-05 13:13:00 mitochondrial creatine kinase expression in hepatocellular carcinoma may be caused by hepatocarcinogenesis per se but not by loss of mitochondrial integrity, of which ASB9 could be a negative regulator 24174293

名称对应

Type IDs
Synonymous CKMT, CKMT1, UMTCK
Gene
UniProtKB-ID: KCRU_HUMAN
UniprotKB: P12532
UniParc: UPI00019153EC, UPI000012DCCE
EMBL: BC006467, BC108652, AK295776, AK223365, BC001926, BC121001, AK316319, AK316124, BT006628, BC121002, J04469
Ensembl: ENSG00000223572, ENSG00000237289
KO: hsa:548596, hsa:1159
Nucleutide sequences
EMBL-CDS: BAG58600.1, AAP35274.1, AAA98744.1, BAH14690.1, AAH06467.1, AAI08653.1, BAH14495.1, AAI21003.1, AAI21002.1, BAD97085.1, AAH01926.1
Ensembl_TRS: ENST00000413453, ENST00000441322, ENST00000300283, ENST00000434505
Protein sequencees
Ensembl_PRO: ENSP00000300283, ENSP00000413255, ENSP00000406577, ENSP00000413165
RefSeq: NP_066270.1, NP_001362413.1, XP_011519498.1, XP_011519497.1, XP_005254207.1, XP_011519501.2, XP_011519496.1, XP_016877391.1, XP_011519500.1
Others
UniRef100: UniRef100_P12532
UniRef90: UniRef90_P25809
UniRef50: UniRef50_P25809
UniGene: Hs.741420
CCDS: CCDS32217.1, CCDS10097.1

全选

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