| Type | Description |
|---|---|
| Definition | DIS3 like exosome 3'-5' exoribonuclease |
| Date | Results | Publications |
|---|---|---|
| 2018-08-04 12:05:00 | we screened the susceptibility loci for Myocardial infarction (MI) using exome sequencing and validated candidate variants in replication sets. We identified that three genes (GYG1, DIS3L and DDRGK1) were associated with MI at the discovery and replication stages. | 29321365 |
| 2010-08-23 12:24:00 | Data indicate that hDis3L1 is a novel exosome-associated exoribonuclease in the cytoplasm of human cells. | 20531389 |
| 2010-08-23 12:23:00 | Data show that hDIS3 and hDIS3L are active exonucleases, but only hDIS3 has retained endonucleolytic activity, and suggest that three different ribonucleases can serve as catalytic subunits for the exosome in human cells. | 20531386 |
| Type | IDs |
|---|---|
| Synonymous | DIS3L1 |
| Gene |
UniProtKB-ID:
DI3L1_HUMAN
UniprotKB:
Q8TF46
UniParc:
UPI000162779D,
UPI0000140545,
UPI0000072E98,
UPI0000EE50A4
EMBL:
AB075835,
BC022089,
CH471082,
AK095407,
BC014124,
AC055855
Ensembl:
ENSG00000166938
KO:
hsa:115752
|
| Nucleutide sequences |
EMBL-CDS:
BAC04542.1,
EAW77759.1,
AAH14124.2,
AAH22089.1,
BAB85541.1
Ensembl_TRS:
ENST00000319212,
ENST00000319194
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000321711,
ENSP00000321583
RefSeq:
XP_005254203.1,
NP_001310865.1,
NP_001310870.1,
NP_001310873.1,
NP_001310872.1,
NP_001137160.1,
NP_001310874.1,
NP_001310866.1,
NP_001310875.1,
NP_001310867.1,
NP_588616.1,
NP_001310869.1,
NP_001310868.1,
NP_001310877.1
|
| Others |
UniRef100:
UniRef100_Q8TF46
UniRef90:
UniRef90_Q8TF46
UniRef50:
UniRef50_Q8TF46
UniGene:
Hs.446251
CCDS:
CCDS10214.1,
CCDS45286.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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