| Type | Description |
|---|---|
| Definition | cysteine-rich secretory protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-11-09 11:57:00 | these results demonstrated that the sustained level of AEG-1 as an important anti-apoptotic factor in nigral dopaminergic (DA) neurons might potentiate the therapeutic effects of treatments, such as Rheb(S16H) administration, on the degeneration of the DA pathway that characterizes Parkinson's disease. | 29670079 |
| 2019-10-26 11:10:00 | These observations reveal that CRISP proteins are relevant for epididymal epithelium differentiation and male fertility, contributing to a better understanding of the fine-tuning mechanisms underlying sperm maturation and immunotolerance in the epididymis with clear implications for human epididymal physiology and pathology. | 30510210 |
| 2019-10-05 10:06:00 | phenotype of CRISP1 null males is modulated by the genetic context and reveal new roles for the protein in both the functional events and signaling pathways associated to sperm capacitation. | 29481619 |
| 2015-12-26 11:58:00 | patch clamping of sperm revealed that CRISP1 has the ability to regulate CatSper, the principal sperm Ca(2+) channel involved in hyperactivation and essential for fertility | 26416967 |
| 2015-02-07 12:12:00 | These results suggest that CRISP1 may be an important structural component of mouse hair and that its strain-specific dysregulation may indicate a predisposition to hair shaft disease such as Alopecia areata | 25446841 |
| Type | IDs |
|---|---|
| Synonymous | AW324342, Aeg1, CRISP-1, SCP 1 |
| Gene |
UniProtKB-ID:
CRIS1_MOUSE,
Q545H0_MOUSE
UniprotKB:
Q03401,
Q545H0
UniParc:
UPI0000003ED2
EMBL:
AK009449,
M92849,
L05559
Ensembl:
ENSMUSG00000025431
KO:
mmu:11571
|
| Nucleutide sequences |
EMBL-CDS:
AAA37185.1,
AAA37460.1,
BAB26295.1
Ensembl_TRS:
ENSMUST00000026498
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000026498
RefSeq:
NP_033768.3
|
| Others |
UniRef100:
UniRef100_Q03401
UniRef90:
UniRef90_Q03401
UniRef50:
UniRef50_Q7T1K6
UniGene:
Mm.16781
CCDS:
CCDS28784.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员