| Type | Description |
|---|---|
| Definition | adrenergic receptor, alpha 2b |
| Date | Results | Publications |
|---|---|---|
| 2017-11-11 14:02:00 | alpha2B KO mice exhibit altered locomotor behaviors and compulsive burying behavior, are acutely sensitive to the stereotypy effects of the psychostimulant amphetamine; an identical tendency in alpha2C KO mice administered the alpha2B-receptor-selective antagonist AGN-209419 with amphetamine. Findings suggest a compulsive phenotype for alpha2B KO mice, and a broader role for the alpha2B receptor. | 27751959 |
| 2016-05-14 10:20:00 | Data indicate that In arrestin 3 deficient mice, where the alpha2B adrenergic receptor has a stronger binding to spinophilin, the hypertensive response is enhanced. | 26244553 |
| 2012-11-03 10:11:00 | Activation of the adenosine A(2B) receptor protects against vascular injury, while it also enhances plaque stability as indicated by increased collagen content. | 22743060 |
| 2012-01-28 12:16:00 | Demonstrate that both A(2A)ARs and A(2B)ARs induce coronary flow changes through K(ATP) channels. | 21949117 |
| 2010-11-27 11:08:00 | alpha(2B)-adrenoceptors in lung epithelia play an important role in suppressing sonic hedgehog-mediated proliferation of mesenchymal cells and thus prevent respiratory failure | 20729197 |
| Type | IDs |
|---|---|
| Synonymous | Adra-2b, [a]2B, a2b-AR, alpha2-C2, alpha2B |
| Gene |
UniProtKB-ID:
F8VQ23_MOUSE,
Q925K6_MOUSE
UniprotKB:
F8VQ23,
Q925K6
UniParc:
UPI00000E7927,
UPI0000022BA6
EMBL:
AF332050,
AL731836
Ensembl:
ENSMUSG00000058620
KO:
mmu:11552
|
| Nucleutide sequences |
EMBL-CDS:
AAK56079.1
Ensembl_TRS:
ENSMUST00000071902,
ENSMUST00000104934
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000071798,
ENSMUSP00000100539
RefSeq:
NP_033763.3
|
| Others |
UniRef100:
UniRef100_F8VQ23
UniRef90:
UniRef90_P19328
UniRef50:
UniRef50_P19328
UniGene:
Mm.347390
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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