| Type | Description |
|---|---|
| Definition | adrenergic receptor, alpha 1a |
| Date | Results | Publications |
|---|---|---|
| 2020-01-25 14:46:00 | results support an arousal circuit whereby noradrenergic transmission at astrocytic alpha1ARs activates wake-promoting ventral Periaquaductal Gray (Dopamine) neurons via glutamate transmission. | 30269865 |
| 2019-11-30 12:21:00 | results suggest that the APJ-enhanced response requires alpha1A-AR to contract vessels coordinately | 31504625 |
| 2019-03-23 12:01:00 | Thinner media and lower alpha1-adrenoceptor expression weaken contractions of breast cancer feed arteries in response to sympathetic activity. We propose that abnormalities in breast cancer arteries can be exploited to modify tumor perfusion and thereby either starve cancer cells or facilitate drug and oxygen delivery during chemotherapy or radiotherapy. | 29566737 |
| 2017-12-16 12:24:00 | In the mouse bleomycin model of right ventricular failure, the alpha1A-adrenergic receptor subtype agonist A61603 prevents right ventricular failure. | 28822963 |
| 2017-11-25 15:22:00 | Synergistically acting agonists and antagonists of G protein-coupled receptors prevent photoreceptor cell degeneration | 27460988 |
| Type | IDs |
|---|---|
| Synonymous | Adra1c |
| Gene |
UniProtKB-ID:
ADA1A_MOUSE,
Q8BXZ4_MOUSE,
Q8BZV1_MOUSE,
Q8BUE5_MOUSE
UniprotKB:
P97718,
Q8BXZ4,
Q8BZV1,
Q8BUE5
UniParc:
UPI00000EA5EA,
UPI00000EA3A3,
UPI00000EAA4E,
UPI0000024E63
EMBL:
CH466535,
AF031431,
AC154693,
AK079597,
AK042759,
AK085653,
AK033490,
S80220,
BC113139,
AC129570
Ensembl:
ENSMUSG00000045875
KO:
mmu:11549
|
| Nucleutide sequences |
EMBL-CDS:
AAB47044.1,
AAC02658.1,
EDL35992.1,
AAI13140.1,
BAC37694.1,
BAC31355.1,
BAC28316.1,
BAC39495.1
Ensembl_TRS:
ENSMUST00000159068,
ENSMUST00000054661,
ENSMUST00000161339,
ENSMUST00000225182,
ENSMUST00000159365
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000124570,
ENSMUSP00000125354,
ENSMUSP00000053703,
ENSMUSP00000153103,
ENSMUSP00000124322
RefSeq:
XP_017171291.1,
XP_017171290.1,
XP_011243228.1,
NP_001258688.1,
XP_036014300.1,
XP_017171289.1,
XP_011243227.1,
XP_036014302.1,
NP_038489.2,
XP_036014301.1,
XP_006518507.1,
NP_001258690.1,
XP_011243225.1,
XP_006518512.1,
XP_011243226.1,
NP_001258689.1
|
| Others |
UniRef100:
UniRef100_Q8BZV1,
UniRef100_Q8BXZ4,
UniRef100_Q8BUE5,
UniRef100_P97718
UniRef90:
UniRef90_Q8BZV1,
UniRef90_Q8BXZ4,
UniRef90_Q8BUE5,
UniRef90_P35348
UniRef50:
UniRef50_P35348-9,
UniRef50_P35348,
UniRef50_Q8BZV1,
UniRef50_Q91175
UniGene:
Mm.57064
CCDS:
CCDS27223.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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