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11544 Adprh

11544

Adprh

ADP-ribosylarginine hydrolase

protein-coding

Mus musculus

基因描述

Type Description
Definition ADP-ribosylarginine hydrolase

研究结论

Date Results Publications
2019-04-27 11:35:00 Intestinal loops derived from female ADP-ribosylarginine hydrolase knockout (ARH1-KO) mice when injected with cholera toxin showed increased fluid accumulation compared to male ARH1-KO mice. 30500844
2011-10-08 10:30:00 ARH1(-/-) and ARH1(+/-) mice spontaneously develop lymphomas, adenocarcinomas, & metastases more frequently than wild-type. Proper control of protein ADP-ribosylation levels affected by ARH1 is essential for cancer suppression. 21697277
2010-01-21 00:00:00 ADP-ribosylarginine hydrolase promoter activity pattern and involvement of Sp transcription factors are consistent with prior observations of widespread hydrolase expression in mammalian tissues. 15893437
2010-01-21 00:00:00 Cholera toxin-catalyzed ADP-ribosylation of cell proteins can be counteracted by ADPRH, which could function as a modifier gene in disease. 17526733

名称对应

Type IDs
Synonymous Arh1
Gene
UniProtKB-ID: ADPRH_MOUSE, Q3U5N4_MOUSE
UniprotKB: P54923, Q3U5N4
UniParc: UPI0000020CAF
EMBL: AK153498, AK171798, AK146280, BC003437, AF244347, L13290
Ensembl: ENSMUSG00000002844
KO: mmu:11544
Nucleutide sequences
EMBL-CDS: AAA37259.1, AAF86223.1, AAH03437.1, BAE32044.1, BAE42669.1, BAE27038.1
Ensembl_TRS: ENSMUST00000002923
Protein sequencees
Ensembl_PRO: ENSMUSP00000002923
RefSeq: NP_031440.1
Others
UniRef100: UniRef100_P54923
UniRef90: UniRef90_P54923
UniRef50: UniRef50_P54923
UniGene: Mm.20047
CCDS: CCDS28167.1

全选

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