| Type | Description |
|---|---|
| Definition | ubiquitin like with PHD and ring finger domains 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:38:00 | UHRF2 promotes intestinal tumorigenesis through stabilization of TCF4 mediated Wnt/beta-catenin signaling. | 32372448 |
| 2019-07-27 10:43:00 | Uncoupling of UHRF2 from the DNA methylation maintenance program is linked to differences in the molecular readout of chromatin signatures that connect UHRF1 to ubiquitination of histone H3. | 29506131 |
| 2019-07-06 12:44:00 | Immunoprecipitation and immunofluorescence staining reveled that UHRF2 combined with p21 in the nucleus. In addition, UHRF2 degraded p21 through ubiquitination and shortened the half-life of p21. | 29923055 |
| 2018-09-08 11:54:00 | UHRF2 may be a negative regulator of EMT and a novel prognostic biomarker for ESCC. | 29909415 |
| 2018-02-10 11:55:00 | UHRF2 expression is reduced in some leukemia cell lines, this correlates with promoter hypermethylation, and similar UHRF2 methylation profiles are seen in primary human leukemia samples. Thus, UHRF2 and 5hmC are widely present in differentiated human tissues, and UHRF2 protein is poorly expressed or mislocalized in diverse human cancers. | 27738314 |
| Type | IDs |
|---|---|
| Synonymous | NIRF, RNF107, TDRD23, URF2 |
| Gene |
UniProtKB-ID:
UHRF2_HUMAN
UniprotKB:
Q96PU4
UniParc:
UPI000016789D,
UPI000006E524
EMBL:
BC028397,
AL133480,
AF274049,
AL137728,
AL353718,
AB071698
Ensembl:
ENSG00000147854
KO:
hsa:115426
|
| Nucleutide sequences |
EMBL-CDS:
AAM33799.1,
CAH56383.1,
BAB68317.1,
AAH28397.1
Ensembl_TRS:
ENST00000276893,
ENST00000468435
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000276893,
ENSP00000434182
RefSeq:
NP_690856.1,
XP_011516006.1,
XP_011516007.1,
XP_016869742.1,
XP_016869743.1
|
| Others |
UniRef100:
UniRef100_Q96PU4
UniRef90:
UniRef90_Q96PU4
UniRef50:
UniRef50_Q96T88
UniGene:
Hs.493401
CCDS:
CCDS6469.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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