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11542 Adora3

11542

Adora3

adenosine A3 receptor

protein-coding

Mus musculus

基因描述

Type Description
Definition adenosine A3 receptor

研究结论

Date Results Publications
2021-02-20 13:35:00 Adenosine A2A and A3 Receptors Are Able to Interact with Each Other. A Further Piece in the Puzzle of Adenosine Receptor-Mediated Signaling. 32709103
2020-04-18 10:04:00 the findings of this study demonstrate that Namodenoson exerts an antiNASH effect mediated via the deregulation of the PI3K/NFkappaB/Wnt/betacatenin signaling pathway. Thus, targeting A3AR may prove to be a novel direction in the pharmacotherapy of NAFLD/NASH. 31638172
2019-11-09 11:04:00 Our studies show for the first time that A3R signaling plays an important role in regulating age-related osteoarthritis. 30088034
2018-01-06 11:25:00 Reduction in nephron number combined with chronic HS intake is associated with oxidative stress, chronic inflammation, and development of hypertension in mice. Absence of adenosine A3 receptor signaling was strongly protective in this novel mouse model of renal and cardiovascular disease. 27431647
2017-12-09 11:53:00 these data demonstrate the involvement of macrophage A3Rs in the proper chemotactic navigation and consequent in vivo clearance of apoptotic cells. Interestingly, loss of A3Rs did not affect the in vivo clearance of apoptotic thymocytes in the dexamethasone-treated thymus. 28188820

名称对应

Type IDs
Synonymous A3AR, A3R, AA3R, ARA3, Gpcr2
Gene
UniProtKB-ID: Q3U4C5_MOUSE
UniprotKB: Q3U4C5
UniParc: UPI0000020AB4
EMBL: AK154312, AC121847
Ensembl: ENSMUSG00000000562
KO: mmu:11542
Nucleutide sequences
EMBL-CDS: BAE32507.1
Ensembl_TRS: ENSMUST00000000574
Protein sequencees
Ensembl_PRO: ENSMUSP00000000574
RefSeq: NP_033761.2
Others
UniRef100: UniRef100_Q3U4C5
UniRef90: UniRef90_P28647
UniRef50: UniRef50_P28647
UniGene: Mm.235024

全选

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研究热度

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