| Type | Description |
|---|---|
| Definition | cytokine inducible SH2 containing protein |
| Date | Results | Publications |
|---|---|---|
| 2020-12-26 13:13:00 | NK cell-derived GM-CSF potentiates inflammatory arthritis and is negatively regulated by CIS. | 32097462 |
| 2019-10-05 11:09:00 | We conclude that the Cish-SH2 domain is essential for PLC-gamma1 regulation in TCR-stimulated CD8(+) T cells. | 29593227 |
| 2019-08-17 11:05:00 | The CISH rs414171 polymorphism is associated significantly with susceptibility to sepsis and multiple organ dysfunction syndrome in traumatic patients, which might prove to be a novel biomarker for indicating risk of infectious outcomes in critically injured patients. | 29920655 |
| 2019-04-06 11:17:00 | These findings suggest that CISH plays a key role in the eosinophilic inflammation associated with bronchial asthma by regulating IL-13-induced CCL26 production. | 30197185 |
| 2018-09-22 11:02:00 | identified P2RX2, KCNQ5, ERBB3 and SOCS3 to be associated with the progression of age-related hearing impairment | 29325454 |
| Type | IDs |
|---|---|
| Synonymous | BACTS2, CIS, CIS-1, G18, SOCS |
| Gene |
UniProtKB-ID:
CISH_HUMAN
UniprotKB:
Q9NSE2
UniParc:
UPI000049DFA1,
UPI00000015F7,
UPI000002A68B
EMBL:
AK313850,
D83532,
AF132297,
BC031590,
BC064354,
CH471055,
AF035947,
AC096920
Ensembl:
ENSG00000114737
KO:
hsa:1154
|
| Nucleutide sequences |
EMBL-CDS:
BAA92328.1,
AAF97410.1,
EAW65128.1,
EAW65129.1,
BAG36578.1,
AAH64354.1,
AAH31590.1,
AAD28471.2
Ensembl_TRS:
ENST00000443053,
ENST00000348721
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000409346,
ENSP00000294173
RefSeq:
NP_037456.5,
XP_011531631.1,
NP_659508.1
|
| Others |
UniRef100:
UniRef100_Q9NSE2
UniRef90:
UniRef90_Q9NSE2
UniRef50:
UniRef50_Q9NSE2
UniGene:
Hs.655334
CCDS:
CCDS2831.1,
CCDS46834.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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