| Type | Description |
|---|---|
| Definition | alcohol dehydrogenase 5 (class III), chi polypeptide |
| Date | Results | Publications |
|---|---|---|
| 2020-06-27 10:27:00 | Data show that aldo-keto reductase family 1 member A1 (AKR1A1) deletion from murine tissues dramatically lowered NADH-dependent GSNOR activity.. | 31649033 |
| 2020-05-16 13:00:00 | nNOS/GSNOR interaction contributes to skeletal muscle differentiation and homeostasis in humans and mice. | 31043586 |
| 2019-11-02 10:36:00 | Our data indicates that nebivolol has no effect on GSNOR activity, nor does nebivolol inhibit thioredoxin reductase, two of the major protein denitrosylases. | 30188599 |
| 2018-10-27 11:22:00 | Site-directed mutagenesis of Akt at Cys224 revealed that S-nitrosylation at this site was pivotal for the reduced phosphorylation at Akt Ser473, which led to impaired Akt signaling. Furthermore, on HHcy challenge, as compared with GSNOR(+/+)ApoE(-/-) littermate controls, GSNOR(-/-)ApoE(-/-) double knockout mice showed reduced T-cell activation with concurrent reduction of atherosclerosis. | 29860106 |
| 2018-05-26 10:09:00 | Data (including data from studies using knockout and transgenic mice) suggest that obesity and diabetes are accompanied by decreases in GSNOR activity in hepatocytes engendering nitrosative stress; obesity promotes S-nitrosylation of lysosomal proteins in liver, thereby impairing lysosomal enzyme activities and compromising autophagy. | 29074597 |
| Type | IDs |
|---|---|
| Synonymous | Adh-5, Adh3, GSNOR |
| Gene |
UniProtKB-ID:
ADHX_MOUSE,
Q6P5I3_MOUSE
UniprotKB:
P28474,
Q6P5I3
UniParc:
UPI00000E9BA1
EMBL:
U48966,
M84147,
U48970,
AK159803,
BC062879,
AK076507,
AK146949,
U48968,
U48965,
U48964,
BC090978,
U48969
Ensembl:
ENSMUSG00000028138
KO:
mmu:11532
|
| Nucleutide sequences |
EMBL-CDS:
BAE27558.1,
AAA68896.1,
AAC52763.1,
AAH90978.1,
BAC36370.1,
BAE35383.1,
AAH62879.2
Ensembl_TRS:
ENSMUST00000005964
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000005964
RefSeq:
NP_001275507.1,
NP_031436.2
|
| Others |
UniRef100:
UniRef100_P28474
UniRef90:
UniRef90_P11766
UniRef50:
UniRef50_P11766
UniGene:
Mm.3874
CCDS:
CCDS17868.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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