| Type | Description |
|---|---|
| Definition | potassium channel tetramerization domain containing 12 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-05 13:01:00 | Bayesian Genome-wide TWAS Method to Leverage both cis- and trans-eQTL Information through Summary Statistics. | 32961112 |
| 2020-01-11 12:08:00 | association of KCTD12 gene and miR-383-binding genes with rumination | 30886212 |
| 2018-12-22 12:23:00 | KCTD12 may exert its inhibitory role in ESCC through the suppression of WNT /NOTCH, stem cell factors, and chromatin remodelers and can be introduced as an efficient therapeutic marker. | 30157793 |
| 2017-11-25 15:41:00 | our study demonstrate that KCTD12 binds to CDC25B and activates CDK1 and Aurora A to facilitate the G2/M transition and promote tumorigenesis and that Aurora A phosphorylates KCTD12 at serine 243 to trigger a positive feedback loop, thereby potentiating the effects of KCTD12. Thus, the KCTD12-CDC25B-CDK1-Aurora A axis has important implications for cancer diagnoses and prognoses. | 28869606 |
| 2017-04-15 12:03:00 | Low KCTD12 expression is associated with uveal melanoma. | 28000887 |
| Type | IDs |
|---|---|
| Synonymous | C13orf2, PFET1, PFETIN |
| Gene |
UniProtKB-ID:
KCD12_HUMAN,
A0A140VJM4_HUMAN
UniprotKB:
Q96CX2,
A0A140VJM4
UniParc:
UPI0000073DDF
EMBL:
CH471093,
BC013764,
HM005413,
AF359381
Ensembl:
ENSG00000178695
KO:
hsa:115207
|
| Nucleutide sequences |
EMBL-CDS:
AAH13764.1,
AAQ15187.1,
EAW80558.1,
AEE61011.1
Gene_ORFName:
hCG_1646360
Ensembl_TRS:
ENST00000377474
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000366694
RefSeq:
NP_612453.1
|
| Others |
UniRef100:
UniRef100_Q96CX2
UniRef90:
UniRef90_Q6WVG3
UniRef50:
UniRef50_Q6WVG3
UniGene:
Hs.644125
CCDS:
CCDS9455.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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