| Type | Description |
|---|---|
| Definition | autophagy related 4A cysteine peptidase |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:12:00 | Overexpression of ATG4a promotes autophagy and proliferation, and inhibits apoptosis in lens epithelial cells via the AMPK and Akt pathways. | 32626969 |
| 2021-02-27 13:49:00 | Long-noncoding RNA MALAT1 sponges microRNA-92a-3p to inhibit doxorubicin-induced cardiac senescence by targeting ATG4a. | 32384281 |
| 2021-02-06 13:58:00 | The insufficiency of ATG4A in macroautophagy. | 32732290 |
| 2020-06-20 10:16:00 | Human HAP1 and HeLa cells lacking ATG4B exhibit a severe but incomplete defect in LC3/GABARAP processing and autophagy. By further genetic depletion of ATG4 isoforms using CRISPR-Cas9 and siRNA we uncover that ATG4A, ATG4C and ATGD all contribute to residual priming activity, which is sufficient to enable lipidation of endogenous GABARAPL1 on autophagic structures. | 30661429 |
| 2018-02-03 11:29:00 | An intron SNP rs807185 in ATG4A might be a protective factor for lung cancer. | 26061994 |
| Type | IDs |
|---|---|
| Synonymous | APG4A, AUTL2 |
| Gene |
UniProtKB-ID:
ATG4A_HUMAN,
B4DEA4_HUMAN
UniprotKB:
Q8WYN0,
B4DEA4
UniParc:
UPI000006F3C3,
UPI000000DCAF,
UPI0000190A6D,
UPI0001627791,
UPI00017A6D02
EMBL:
AJ320508,
AJ504651,
AK293533,
BC061696,
AJ320509,
AB066214,
BC041862,
AL031177,
CH471120,
AK314429
Ensembl:
ENSG00000101844
KO:
hsa:115201
|
| Nucleutide sequences |
EMBL-CDS:
EAX02693.1,
CAC69076.1,
AAH61696.1,
EAX02691.1,
AAH41862.1,
BAG37044.1,
EAX02689.1,
CAC69077.1,
CAD43218.1,
BAB83889.1,
BAG57015.1
Ensembl_TRS:
ENST00000372232,
ENST00000345734
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000361306,
ENSP00000298131
RefSeq:
XP_011529144.1,
NP_840055.1,
NP_001308218.1,
NP_443168.2,
NP_001308216.1,
NP_840054.1,
NP_001308219.1,
NP_001308217.1
|
| Others |
UniRef100:
UniRef100_B4DEA4,
UniRef100_Q8WYN0
UniRef90:
UniRef90_Q8WYN0,
UniRef90_B4DEA4
UniRef50:
UniRef50_A0A5F4DFF9,
UniRef50_Q8WYN0
UniGene:
Hs.8763
CCDS:
CCDS14538.1,
CCDS14539.1
|
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|---|---|---|---|---|---|---|---|---|
| Refseq |
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