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11518 Add1

11518

Add1

adducin 1 (alpha)

protein-coding

Mus musculus

基因描述

Type Description
Definition adducin 1 (alpha)

研究结论

Date Results Publications
2021-04-17 13:18:00 miR-135a-5p mediates memory and synaptic impairments via the Rock2/Adducin1 signaling pathway in a mouse model of Alzheimer's disease. 33771994
2017-11-26 00:38:00 Sez6l2 is one of the auxiliary subunits of the AMPA receptor and acts as a scaffolding protein to link GluR1 to ADD. Furthermore, Sez6l2 overexpression upregulates ADD phosphorylation, whereas siRNA-mediated downregulation of Sez612 prevents ADD phosphorylation, suggesting that Sez6l2 modulates AMPA-ADD signal transduction. 29032200
2017-11-04 12:47:00 Reduction in ADD1 protein in NEK1 mutant mice is associated with hyperphosphorylation of ADD1, thereby preventing the interaction with MYO10 during meiotic spindle formation 28982183
2017-01-14 11:55:00 adducin activity is not essential for actin ring assembly and periodicity but is necessary to control the diameter of both actin rings and axons and actin filament growth within rings. 27068466
2013-06-22 12:07:00 Targeted deletion of Add1 reveals strain-dependent hyperkyphosis and megaesophagus in c57bl, 129s1 and B6 mice. 22926980

名称对应

Type IDs
Synonymous AI256389
Gene
UniProtKB-ID: ADDA_MOUSE, F8WHZ9_MOUSE, E9Q1K3_MOUSE, F8WGR0_MOUSE
UniprotKB: Q9QYC0, F8WHZ9, E9Q1K3, F8WGR0
UniParc: UPI00015AA247, UPI0000020B1D, UPI00015AA249, UPI00015AA24A, UPI0000021043
EMBL: AF189771, AF096839, AC115695
Ensembl: ENSMUSG00000029106
KO: mmu:11518
Nucleutide sequences
EMBL-CDS: AAF24971.1, AAF29504.1
Ensembl_TRS: ENSMUST00000114340, ENSMUST00000114338, ENSMUST00000052836, ENSMUST00000114335, ENSMUST00000001108
Protein sequencees
Ensembl_PRO: ENSMUSP00000109979, ENSMUSP00000109977, ENSMUSP00000052266, ENSMUSP00000109974, ENSMUSP00000001108
RefSeq: XP_006503733.1, XP_006503738.1, XP_006503741.1, XP_030109929.1, NP_001318010.1, XP_006503740.1, XP_030109932.1, XP_006503743.1, XP_036020632.1, NP_001318012.1, XP_006503732.1, XP_030109930.1, NP_001095914.1, XP_030109931.1, NP_001318013.1, NP_001318009.1, NP_001019629.2, NP_001318015.1, XP_006503742.1, NP_038485.1, XP_030109925.1, XP_036020633.1, XP_006503737.1, XP_006503739.1, NP_001318011.1, NP_001318016.1, XP_030109933.1, NP_001318014.1, XP_030109928.1, XP_030109927.1, XP_017176104.1, XP_036020634.1
Others
UniRef100: UniRef100_Q9QYC0, UniRef100_E9Q1K3, UniRef100_F8WHZ9, UniRef100_F8WGR0
UniRef90: UniRef90_Q9QYC0, UniRef90_F8WGR0
UniRef50: UniRef50_Q9QYC0
UniGene: Mm.289106
CCDS: CCDS39069.1, CCDS19216.1

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