| Type | Description |
|---|---|
| Definition | adenylate cyclase 8 |
| Date | Results | Publications |
|---|---|---|
| 2020-03-21 11:13:00 | FXR is a critical transcription factor that mediates ADCY8 expression in pancreatic beta-cells and the chromatin modification associated with Adcy8 transcription. | 31485455 |
| 2017-11-11 13:32:00 | Genetic deletion of AC8 (adenylyl cyclase 8) but not AC1 abolished long-lasting anxiety. | 27234425 |
| 2016-12-17 12:02:00 | Dysregulation of a survival pathway in adenylyl cyclase 1 and 8 knockout mice was identified following early-life ethanol exposure. | 26992697 |
| 2016-10-01 11:18:00 | Study shows that AC8 is involved in epileptogenesis, and may serve as a potential target for the treatment of epilepsy | 26656781 |
| 2015-12-05 11:40:00 | ADCY8 is required for the physiological activation of glucose-induced signalling pathways in beta cells, for glucose tolerance and for hypothalamic adaptation to a high-fat diet via regulation of islet insulin secretion. | 25403481 |
| Type | IDs |
|---|---|
| Synonymous | AC8, AW060868 |
| Gene |
UniProtKB-ID:
ADCY8_MOUSE,
Q3UUN2_MOUSE,
A0A2I3BQ46_MOUSE
UniprotKB:
P97490,
Q3UUN2,
A0A2I3BQ46
UniParc:
UPI0003D74EAA,
UPI00005ABE08,
UPI0000021EBA
EMBL:
CH466545,
AK138244,
AC160934,
U85021,
AC116996
Ensembl:
ENSMUSG00000022376
KO:
mmu:11514
|
| Nucleutide sequences |
EMBL-CDS:
AAB41885.1,
EDL29361.1,
EDL29360.1,
BAE23593.1
Ensembl_TRS:
ENSMUST00000023007,
ENSMUST00000228014
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000023007,
ENSMUSP00000154029
RefSeq:
NP_001278832.1,
NP_033753.2,
NP_001318004.1
|
| Others |
UniRef100:
UniRef100_A0A2I3BQ46,
UniRef100_P97490
UniRef90:
UniRef90_P97490
UniRef50:
UniRef50_P40146
UniGene:
Mm.1425
CCDS:
CCDS27506.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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