| Type | Description |
|---|---|
| Definition | a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-26 13:14:00 | ADAMTS1 and HSPG2 mRNA levels in cumulus cells are related to human oocyte quality and controlled ovarian hyperstimulation outcomes. | 31974739 |
| 2019-10-26 10:43:00 | These results confirmed a pro-inflammatory landscape in the absence of ADAMTS1, correlating with tumour blockade, supporting its novel role as a modulator of the immune cell response. | 30166561 |
| 2018-03-10 11:27:00 | The developmental arrest of early secondary follicles following furin disruption might be rooted in the loss of the mature form of ADAMTS1 and compromised proliferation of granulosa cells in mutant mice. | 28569793 |
| 2018-01-20 12:06:00 | Data show that NOTCH1 is a target of ADAMTS1 metalloproteinase activity, which reduces Notch signaling, leading to increased satellite cell activation. | 28939843 |
| 2018-01-06 10:47:00 | Reduced tumors in ADAMTS1 knockout mice displayed a paradoxical increase in vascular density and vascular-related genes; a detailed characterization revealed an impaired vasculature, along with a minor infiltration of macrophages. melanoma xenografts showed a relevant induction of its expression in stroma compartments. | 27120788 |
| Type | IDs |
|---|---|
| Synonymous | ADAM-TS1, ADAMTS, ADAMTS-1, C3-C5, METH-1, METH1 |
| Gene |
UniProtKB-ID:
ATS1_MOUSE,
Q3TTE6_MOUSE,
Q3TQF7_MOUSE
UniprotKB:
P97857,
Q3TTE6,
Q3TQF7
UniParc:
UPI00005B1FAC,
UPI000002203D,
UPI00005B1D44
EMBL:
AB001735,
D67076,
AK161409,
AK163622,
AC126936,
BC050834,
BC040382
Ensembl:
ENSMUSG00000022893
KO:
mmu:11504
|
| Nucleutide sequences |
EMBL-CDS:
BAA24501.1,
AAH40382.1,
AAH50834.1,
BAA11088.1,
BAE36379.1,
BAE37426.1
Ensembl_TRS:
ENSMUST00000023610
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000023610
RefSeq:
NP_033751.3
|
| Others |
UniRef100:
UniRef100_P97857,
UniRef100_Q3TTE6
UniRef90:
UniRef90_Q3TTE6,
UniRef90_P97857
UniRef50:
UniRef50_Q9ESP7,
UniRef50_P97857
UniGene:
Mm.1421
CCDS:
CCDS28287.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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