| Type | Description |
|---|---|
| Definition | solute carrier family 26 member 9 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-25 11:03:00 | findings indicate that an increase in SLC26A9 expression in ductal cells of the pancreas delays the age at onset of diabetes, suggesting a CFTR-agnostic treatment for a major complication of CF. | 31581148 |
| 2020-06-27 11:53:00 | The anion-conducting transporter solute carrier family 26 member 9 (SLC26A9) localizes to the tight junction in well-differentiated bronchi epithelial cell from non-cystic fibrosis (CF) patients, suggesting that F508del-CF transmembrane conductance regulator (CFTR) enhances proteasomal SLC26A9 degradation. | 31645438 |
| 2018-03-03 11:48:00 | Treatment response to ivacaftor, which aims to improve CFTR-channel opening probability in cystic fibrosis patients with gating mutations, shows substantial variability in response, 28% of which can be explained by rs7512462 in SLC26A9. | 28171547 |
| 2017-08-05 12:41:00 | when SLC26A9 is coexpressed with F508del CFTR, its trafficking defect leads to a PDZ motif-sensitive intracellular retention of SLC26A9. | 28360110 |
| 2015-07-04 10:14:00 | SLC26A9 single nucleotide polymorphisms modify prenatal exocrine pancreatic damage in cystic fibrosis | 25771386 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
S26A9_HUMAN,
B3KXK1_HUMAN
UniprotKB:
Q7LBE3,
B3KXK1
UniParc:
UPI000014028B,
UPI000013DF98,
UPI00004A2860
EMBL:
AF331525,
AL713965,
BC136538,
BC151208,
CH471067,
AF314958,
AK127491
Ensembl:
ENSG00000174502
KO:
hsa:115019
|
| Nucleutide sequences |
EMBL-CDS:
AAK95667.1,
AAL26867.1,
AAI51209.1,
EAW91588.1,
EAW91587.1,
AAI36539.1,
BAG54513.1
Ensembl_TRS:
ENST00000367134,
ENST00000340781,
ENST00000367135
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000356102,
ENSP00000356103,
ENSP00000341682
RefSeq:
XP_011507423.1,
NP_599152.2,
NP_443166.1,
XP_011507424.1,
XP_011507426.1
|
| Others |
UniRef100:
UniRef100_B3KXK1,
UniRef100_Q7LBE3
UniRef90:
UniRef90_Q7LBE3,
UniRef90_B3KXK1
UniRef50:
UniRef50_A0A2F0BJC8,
UniRef50_Q8BU91
UniGene:
Hs.164073
CCDS:
CCDS30989.1,
CCDS30990.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员