| Type | Description |
|---|---|
| Definition | a disintegrin and metallopeptidase domain 8 |
| Date | Results | Publications |
|---|---|---|
| 2019-09-28 11:52:00 | ADAMs binds to integrins to regulate cell adhesion and migration. | 29750543 |
| 2019-07-06 10:03:00 | In mice, Adam8 was highly expressed in circulating neutrophils and in macrophages. Moreover, ADAM8 deficient mouse macrophages displayed reduced secretion of inflammatory mediators. Remarkably, however, neither hematopoietic nor whole-body ADAM8 deficiency in mice affected atherosclerotic lesion size. | 28916789 |
| 2019-02-16 11:23:00 | Gene expression of adam8 was elevated at all time points after injury. | 28863006 |
| 2017-09-23 10:22:00 | ADAM8 on leukocytes holds a proinflammatory function in acute lung inflammation by promoting alveolar leukocyte recruitment. | 28596294 |
| 2016-08-06 10:35:00 | The important role of ADAM8 in the progression of hepatocellular carcinoma induced by diethylnitrosamine in mice | 25585999 |
| Type | IDs |
|---|---|
| Synonymous | ADAM 8, CD156, CD156a, E430039A18Rik, MS2 |
| Gene |
UniProtKB-ID:
ADAM8_MOUSE,
Q3U1J7_MOUSE,
Q3U7G2_MOUSE
UniprotKB:
Q05910,
Q3U1J7,
Q3U7G2
UniParc:
UPI0000357AD3,
UPI000002798A
EMBL:
AK155912,
AK152675,
X13335,
AK150411,
D10911,
AC107822
Ensembl:
ENSMUSG00000025473
KO:
mmu:11501
|
| Nucleutide sequences |
EMBL-CDS:
BAA21771.1,
CAA31712.1,
BAE29535.1,
BAE33500.1,
BAE31407.1
Ensembl_TRS:
ENSMUST00000106069,
ENSMUST00000026546
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000101684,
ENSMUSP00000026546
RefSeq:
XP_006536214.1,
NP_031429.1,
NP_001277995.1,
XP_017177421.1,
XP_017177423.1,
XP_017177422.1
|
| Others |
UniRef100:
UniRef100_Q05910,
UniRef100_Q3U7G2
UniRef90:
UniRef90_Q05910
UniRef50:
UniRef50_Q05910
UniGene:
Mm.15969
CCDS:
CCDS21959.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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