| Type | Description |
|---|---|
| Definition | a disintegrin and metallopeptidase domain 22 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-27 12:15:00 | Results have identified ADAM22 as the most potential target of miR-221, and silencing ADAM22 resulted in a reduced foam cell formation and cell apoptosis. | 30362166 |
| 2019-09-28 10:04:00 | ADAM22 negatively regulates cardiac myocyte AKT activation and the process of cardiac hypertrophy. | 29358191 |
| 2015-10-31 10:23:00 | LGI1 and ADAM22 form an essential synaptic organizing complex that coordinates the maturation of excitatory synapses by regulating the functional incorporation of PSD-95 | 26178195 |
| 2015-08-22 10:49:00 | Interaction proteomics revealed the interactors of Caspr2, including CNTN2, KCNAs, members of the ADAM family (ADAM22, ADAM23 and ADAM11), members of LGI family and MAGUKs (DLGs and MPPs). | 25707359 |
| 2010-02-08 11:43:00 | ADAM22 is an axonal component of the Kv1 K+ channel complex that recruits membrane-associated guanylate kinase to juxtaparanodes | 20089912 |
| Type | IDs |
|---|---|
| Synonymous | 2900022I03Rik, AI854032, MDC2 |
| Gene |
UniProtKB-ID:
ADA22_MOUSE,
D6QSS8_MOUSE,
D3YUP9_MOUSE
UniprotKB:
Q9R1V6,
D6QSS8,
D3YUP9
UniParc:
UPI0000D60DC5,
UPI0000D60DC7,
UPI0000D60DC9,
UPI00000265A3,
UPI0000D77AAC,
UPI000002951D,
UPI0000D60DC3,
UPI0000D60DCD,
UPI0000D60DC0,
UPI0000D60DCA,
UPI0000D60DC4,
UPI0000D60DCF,
UPI0000D60DBF,
UPI0000D60DC6,
UPI0000D60DC8,
UPI000043539B,
UPI000002A351,
UPI0000D60DCC,
UPI0000D60DC2,
UPI0000D60DCE,
UPI0000D60DCB,
UPI0000D60DC1
EMBL:
AB179849,
AB179856,
AB179846,
AB179855,
AC152165,
AB179861,
AB179857,
AB009674,
AK034528,
AC156022,
AB179847,
AB179854,
AB179858,
AB179851,
AB179859,
AB179853,
AB179848,
AB179850,
AB179844,
AB179843,
AB179860,
HM004095,
AB179842,
AB179845,
AB179862,
AB179852,
AC140364
Ensembl:
ENSMUSG00000040537
KO:
mmu:11496
|
| Nucleutide sequences |
EMBL-CDS:
BAD72814.1,
BAD72811.1,
BAD72817.1,
BAD72807.1,
BAD72810.1,
BAD72823.1,
BAD72812.1,
BAD72821.1,
BAD72819.1,
BAC28742.1,
BAD72808.1,
BAD72816.1,
BAD72809.1,
BAA83383.1,
BAD72822.1,
BAD72805.1,
BAA83382.1,
BAD72818.1,
BAD72804.1,
BAD72813.1,
BAD72815.1,
BAD72803.1,
BAD72820.1,
BAD72806.1,
ADG21259.1
Ensembl_TRS:
ENSMUST00000050166,
ENSMUST00000088761,
ENSMUST00000046838,
ENSMUST00000115388,
ENSMUST00000088744,
ENSMUST00000115386
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000049120,
ENSMUSP00000086139,
ENSMUSP00000055000,
ENSMUSP00000086122,
ENSMUSP00000111046,
ENSMUSP00000111044
RefSeq:
NP_001297368.1,
XP_006503600.1,
XP_006503599.1,
NP_001297369.1,
XP_006503595.1,
XP_006503596.1,
XP_006503598.1,
XP_030109924.1,
XP_006503594.1,
XP_036020631.1,
XP_006503591.1,
NP_001091695.1,
XP_006503593.1,
NP_001007222.1,
NP_001007221.1,
XP_006503605.1,
XP_006503592.1,
XP_006503603.1,
XP_006503597.1
|
| Others |
UniRef100:
UniRef100_Q9R1V6,
UniRef100_D3YUP9
UniRef90:
UniRef90_Q9R1V6,
UniRef90_Q9R1V6-1
UniRef50:
UniRef50_Q9R1V6
UniGene:
Mm.275895
CCDS:
CCDS80205.1,
CCDS51411.1,
CCDS80207.1,
CCDS19080.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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