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114907 FBXO32

114907

FBXO32

F-box protein 32

protein-coding

Homo sapiens

基因描述

Type Description
Definition F-box protein 32

研究结论

Date Results Publications
2018-10-06 12:24:00 F-box only protein 32 (FBXO32) directly ubiquitinates C-terminal binding protein 1 (CtBP1), which is required for its stability and nuclear retention. 29142217
2018-09-01 11:48:00 Authors found that the FBXO32 and SMAD4 levels were higher in normal tissues than in CRC tissues. The expressions of FBXO32 and SMAD4 were related to clinicopathological parameters in CRC. 29465067
2017-12-23 12:43:00 role of the muscle specific E3s MuRF-1 and MAFbx in skeletal muscle wasting during various pathologies, as well as their regulation by modifiable lifestyle factors, were explored (review) 26738803
2017-12-02 10:54:00 FBXO32 activates NF-kappaB through IkappaBalpha degradation in inflammatory and genotoxic stress 28970077
2017-11-25 15:58:00 Transcriptional analysis of endophilin-A mutant mice, complemented by proteomics, highlighted ataxia- and protein-homeostasis-related genes and revealed upregulation of the E3-ubiquitin ligase FBXO32/atrogin-1 and its transcription factor FOXO3A. 27720640

名称对应

Type IDs
Synonymous Fbx32, MAFbx
Gene
UniProtKB-ID: FBX32_HUMAN, A0A024R9F3_HUMAN, Q498Y9_HUMAN, Q0VAQ6_HUMAN, I6L984_HUMAN
UniprotKB: Q969P5, A0A024R9F3, Q498Y9, Q0VAQ6, I6L984
UniParc: UPI0000034E28, UPI000059059D, UPI0000070299, UPI000021055A, UPI0000161195
EMBL: BC120963, EF143260, AC090193, BC100020, BC120964, AY059629, AK056986, CH471060, AJ420108, BC024030
Ensembl: ENSG00000156804
KO: hsa:114907
Nucleutide sequences
EMBL-CDS: ABO37797.1, AAL16407.1, CAD12251.1, BAB71333.1, EAW92043.1, EAW92042.1, AAI00021.1, AAI20965.1, AAI20964.1, AAH24030.1
Gene_ORFName: hCG_21393
Ensembl_TRS: ENST00000517956, ENST00000443022
Protein sequencees
Ensembl_PRO: ENSP00000390790, ENSP00000428205
RefSeq: NP_478136.1, NP_001229392.1, NP_680482.1
Others
UniRef100: UniRef100_Q0VAQ6, UniRef100_Q969P5, UniRef100_I6L984
UniRef90: UniRef90_Q0VAQ6, UniRef90_I6L984, UniRef90_Q969P5
UniRef50: UniRef50_Q969P5, UniRef50_A0A6I8PFB7, UniRef50_A0A4W5KHE3
UniGene: Hs.403933
CCDS: CCDS56553.1, CCDS6345.1

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