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11490 Adam15

11490

Adam15

a disintegrin and metallopeptidase domain 15 (metargidin)

protein-coding

Mus musculus

基因描述

Type Description
Definition a disintegrin and metallopeptidase domain 15 (metargidin)

研究结论

Date Results Publications
2020-10-10 13:00:00 ADAM (a Disintegrin and Metalloproteinase) 15 Deficiency Exacerbates Ang II (Angiotensin II)-Induced Aortic Remodeling Leading to Abdominal Aortic Aneurysm. 32522006
2019-12-14 10:49:00 endothelial progenitor cells (EPCs) transplantation exerted its therapeutic effect of acute lung injury (ALI) via increasing miR-10a/b-5p and reducing ADAM15, thus providing a novel insight into the molecular mechanism of EPC transplantation in treating ALI 31174540
2019-10-26 12:12:00 ADAM15 has a critical role in mediating vascular barrier dysfunction during inflammation. Its mechanisms of action involve CD44 shedding and endothelial glycocalyx injury. 29939250
2015-12-05 11:26:00 findings indicated that silencing ADAM15 had antiinflammatory effects in FLSs and efficiently inhibited the development of CIA. 25650586
2014-12-27 11:20:00 the catalytic activity of ADAM15 is not crucial for its function in promoting pathological neovascularization in the mouse OIR model, most likely because of the very limited substrate repertoire of ADAM15. 25249606

名称对应

Type IDs
Synonymous AD56, MDC15
Gene
UniProtKB-ID: ADA15_MOUSE
UniprotKB: O88839
UniParc: UPI00000E995B, UPI0000029C99, UPI00000E63D2, UPI000021FC3E
EMBL: AK048901, AK149796, BC009132, AF006196, AK151804, EF506571, AB022089, AK152725, AK170101
Ensembl: ENSMUSG00000028041
KO: mmu:11490
Nucleutide sequences
EMBL-CDS: BAA88903.1, BAE29090.1, BAC33485.1, BAE30703.1, AAC61896.1, BAE31447.1, ABP73662.1, AAH09132.1, BAE41564.1
Ensembl_TRS: ENSMUST00000074582, ENSMUST00000184651, ENSMUST00000107448, ENSMUST00000107446, ENSMUST00000029676
Protein sequencees
Ensembl_PRO: ENSMUSP00000029676, ENSMUSP00000139147, ENSMUSP00000103072, ENSMUSP00000103070, ENSMUSP00000074167
RefSeq: XP_006500981.1, NP_033744.1, NP_001032811.2
Others
UniRef100: UniRef100_O88839
UniRef90: UniRef90_O88839
UniRef50: UniRef50_Q13444
UniGene: Mm.274049, Mm.470104
CCDS: CCDS17503.1, CCDS17502.1

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