| Type | Description |
|---|---|
| Definition | DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) |
| Date | Results | Publications |
|---|---|---|
| 2019-09-28 11:55:00 | Spermatozoa in DCUN1D1-/- mice had multiple abnormalities, including globozoospermia, macrocephaly, and multiple flagella. | 30653527 |
| 2017-09-30 11:51:00 | Data (including data from studies using cells cultured from knockout mice) suggest that Sccro neddylates Cul3 with Nedd8, promoting Cul3/Klhl21 complex formation and localization of Cul3 during telophase. (Sccro = squamous cell carcinoma-related oncogene; Cul3 = cullin 3; Nedd8 = neural precursor cell expressed, developmentally down-regulated protein 8; Klhl21 = kelch-like protein 21) | 28620047 |
| 2016-08-13 10:51:00 | SCCRO family members cooperatively regulate neddylation and cell proliferation. | 26792857 |
| 2015-04-11 10:21:00 | The ubiquitin-associated (UBA) domain of SCCRO/DCUN1D1 protein serves as a feedback regulator of biochemical and oncogenic activity. | 25411243 |
| 2011-06-18 11:17:00 | in the nucleus, SCCRO enhances recruitment of Ubc12 to Cul1 to promote neddylation | 21247897 |
| Type | IDs |
|---|---|
| Synonymous | Rp42, SCCRO, Tes3, pTes3 |
| Gene |
UniProtKB-ID:
DCNL1_MOUSE,
Q3UT23_MOUSE
UniprotKB:
Q9QZ73,
Q3UT23
UniParc:
UPI0000029EF2,
UPI00001C2B2E
EMBL:
AK165651,
BC020161,
AK139845,
AK155081,
BC031666,
AF198092,
AC116677,
BC037431,
AK029314,
AK008657
Ensembl:
ENSMUSG00000027708
KO:
mmu:114893
|
| Nucleutide sequences |
EMBL-CDS:
AAH20161.1,
AAF04863.1,
BAE38318.1,
AAH31666.1,
AAH37431.1,
BAE33033.1,
BAC26390.1,
BAB25813.1,
BAE24157.1
Ensembl_TRS:
ENSMUST00000108182,
ENSMUST00000198389,
ENSMUST00000178098
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000103817,
ENSMUSP00000143243,
ENSMUSP00000137324
RefSeq:
XP_006535437.1,
NP_001192290.1,
NP_296372.3,
NP_001192291.1,
XP_036018755.1
|
| Others |
UniRef100:
UniRef100_Q9QZ73,
UniRef100_Q3UT23
UniRef90:
UniRef90_Q9QZ73
UniRef50:
UniRef50_Q96GG9
UniGene:
Mm.374810,
Mm.379305,
Mm.474495
CCDS:
CCDS57207.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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