| Type | Description |
|---|---|
| Definition | oxysterol binding protein like 1A |
| Date | Results | Publications |
|---|---|---|
| 2019-04-13 11:09:00 | ORP1 is a unique sensor of lysosomal phosphatidylinosito-bisphosphates, and that PI(4,5)P2/PI(3,4)P2 allosterically regulates cholesterol transport by ORP1. | 30783101 |
| 2019-03-02 12:02:00 | structural and biochemical investigation of the Rab7-ORP1L interaction | 30012887 |
| 2018-09-01 10:45:00 | ORP1L, via its liganding by lipids and the formation of contacts between autophagic vacuoles and the endoplasmic reticulum, governs the last steps in autophagy that lead to the lysosomal degradation of cytosolic material. | 27283760 |
| 2018-07-21 11:57:00 | This study validated that rs3746444 polymorphism influenced the expression of miR499a, its target gene, osbpl1a, and thereby associated with the HDL level, which makes it a potential factor involved in the mechanism of atherosclerosis. | 29039586 |
| 2018-03-10 10:53:00 | ORP1L-dependent membrane contacts between late endosomes/lysosomes and the endoplasmic reticulum coordinate cholesterol transfer with the retrograde movement of endo-lysosomal vesicles. | 28564600 |
| Type | IDs |
|---|---|
| Synonymous | ORP-1, ORP1, OSBPL1B |
| Gene |
UniProtKB-ID:
OSBL1_HUMAN,
Q6GSK5_HUMAN,
B3KU11_HUMAN,
B0YJ56_HUMAN
UniprotKB:
Q9BXW6,
Q6GSK5,
B3KU11,
B0YJ56
UniParc:
UPI00019152C1,
UPI0000130E95,
UPI000002B029,
UPI00005A6D2B
EMBL:
CH471088,
BC098384,
AC090772,
AF323726,
BC063420,
AF274714,
AK301862,
AK096358,
AC023983,
AF392450,
AF392449,
BC136452,
EF445004,
AK001079
Ensembl:
ENSG00000141447
KO:
hsa:114876
|
| Nucleutide sequences |
EMBL-CDS:
AAK15154.1,
AAL40662.1,
AAG53407.2,
AAL40663.1,
BAH13569.1,
AAH63420.1,
AAH98384.1,
EAX01183.1,
ACA06035.1,
BAG53273.1,
ACA06034.1,
EAX01182.1,
AAI36453.1
Gene_ORFName:
hCG_2020467,
hCG_2020467
Ensembl_TRS:
ENST00000399443,
ENST00000319481,
ENST00000357041
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000349545,
ENSP00000382372,
ENSP00000320291
RefSeq:
NP_001229437.1,
XP_006722443.1,
XP_016881019.1,
XP_006722445.1,
NP_542164.2,
XP_016881021.1,
NP_060500.3,
XP_016881022.1,
XP_016881020.1
|
| Others |
UniRef100:
UniRef100_B3KU11,
UniRef100_Q9BXW6
UniRef90:
UniRef90_Q9BXW6
UniRef50:
UniRef50_Q9BXW6
UniGene:
Hs.370725
CCDS:
CCDS11885.1,
CCDS11884.1,
CCDS56056.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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