| Type | Description |
|---|---|
| Definition | phospholipase C, zeta 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-11-24 10:48:00 | PLCzeta1 is a sperm-borne oocyte activation factor that ensures oocyte activation steps for monospermic fertilization. | 29358633 |
| 2016-04-23 11:55:00 | analysis of the EF-hand domain in targeting sperm phospholipase Czeta to membrane phosphatidylinositol 4,5-bisphosphate | 26429913 |
| 2015-01-03 12:28:00 | Human PLCzeta exhibits superior fertilization potency over mouse PLCzeta in triggering the Ca(2+) oscillations required for mammalian oocyte activation. | 24478462 |
| 2012-07-14 10:33:00 | these results suggest that both PLCzeta- and sperm-mediated Ca2+ release preferentially use an intracellular membranous source of PI(4,5)P2, in contrast to PLCdelta1, which targets PI(4,5)P2 in the plasma membrane. | 22114355 |
| 2011-12-17 11:40:00 | Data suggest that positively charged residues within the XY linker play an important role in the PLCzeta interaction with PtdIns(4,5)P(2), a crucial step in generating the Ca(2+) activation signal that is essential for fertilization in mammals. | 21730019 |
| Type | IDs |
|---|---|
| Synonymous | 1700041H07Rik, PLCzeta |
| Gene |
UniProtKB-ID:
PLCZ1_MOUSE
UniprotKB:
Q8K4D7
UniParc:
UPI0000028BF6,
UPI000002342F
EMBL:
BC106767,
AK006672,
AF435950
Ensembl:
ENSMUSG00000030230
KO:
mmu:114875
|
| Nucleutide sequences |
EMBL-CDS:
AAI06768.1,
AAM95914.1
Ensembl_TRS:
ENSMUST00000032356
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000032356
RefSeq:
XP_006506967.1,
XP_006506964.1,
XP_030110971.1,
XP_006506965.1,
XP_006506963.1,
NP_473407.2,
XP_006506962.1,
XP_017176832.1
|
| Others |
UniRef100:
UniRef100_Q8K4D7
UniRef90:
UniRef90_Q8K4D7
UniRef50:
UniRef50_Q8K4D7
UniGene:
Mm.50808
CCDS:
CCDS20671.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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