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114836 SLAMF6

114836

SLAMF6

SLAM family member 6

protein-coding

Homo sapiens

基因描述

Type Description
Definition SLAM family member 6

研究结论

Date Results Publications
2020-02-29 10:07:00 SLAMF6 is an important regulator of T cell activation where both its ectodomain and its endodomain contribute differentially to T cell functions. 31199820
2019-03-16 13:08:00 Authors found that seSLAMF6 reduced activation-induced cell death and had an antiapoptotic effect on tumor-infiltrating lymphocytes. 29305520
2018-06-23 11:54:00 these results showed that the NTB-A/SAP pathway regulates T-cell activation and restimulation-induced cell death during human tuberculosis 28546549
2017-09-23 10:17:00 in addition to its established role in Invariant NKT(iNKT) cell ontogeny, Ly108 regulates iNKT cell function in mice and humans 28373584
2016-08-13 10:09:00 In addition to their role in NK cell activation by hematopoietic cells, the SLAM-SAP-SHP1 pathways influence responsiveness toward nonhematopoietic targets by a process akin to NK cell 'education'. 26878112

名称对应

Type IDs
Synonymous CD352, KALI, KALIb, Ly108, NTB-A, NTBA, SF2000
Gene
UniProtKB-ID: SLAF6_HUMAN, B4E1U5_HUMAN
UniprotKB: Q96DU3, B4E1U5
UniParc: UPI0000051E34, UPI000046FD75, UPI000004D14E, UPI00017A87AC
EMBL: AK313549, BC114495, AK125624, AK301026, AK303990, AY358159, BC113893, AL138930, AL832854, CH471121, AJ306388, AJ277141
Ensembl: ENSG00000162739
KO: hsa:114836
Nucleutide sequences
EMBL-CDS: CAC59749.1, AAI14496.1, CAC59750.1, CAI46161.1, BAG62642.1, BAG36325.1, AAI13894.1, BAG54223.1, EAW52715.1, AAQ88526.1, EAW52713.1, BAG64907.1
Gene_ORFName: UNQ6123/PRO20080
Ensembl_TRS: ENST00000368059, ENST00000368055, ENST00000368057
Protein sequencees
Ensembl_PRO: ENSP00000357034, ENSP00000357036, ENSP00000357038
RefSeq: NP_001171643.1, NP_001171644.1, NP_001171645.1, XP_016855706.1, XP_016855704.1, NP_443163.1, XP_016855705.1
Others
UniRef100: UniRef100_Q96DU3, UniRef100_B4E1U5
UniRef90: UniRef90_Q96DU3
UniRef50: UniRef50_Q96DU3
UniGene: Hs.492348
CCDS: CCDS53393.1, CCDS1205.1, CCDS53394.1

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