| Type | Description |
|---|---|
| Definition | PWWP domain containing 2A |
| Date | Results | Publications |
|---|---|---|
| 2020-05-30 12:56:00 | It has been shown that dysregulation of the circular RNA PWWP2A-miR-579 axis is involved in dexamethasone-induced cytotoxicity in human osteoblasts. | 31376935 |
| 2019-01-19 11:40:00 | PWWP2A is a complex chromatin-binding protein that serves to direct the deacetylase complex M1HR to H2A.Z-containing chromatin, thereby promoting changes in histone acetylation levels.PWWP2A's internal region binds H2A.Z nucleosomes and DNA. | 30327463 |
| 2019-01-19 10:07:00 | Study in HeLa, HEK293F, and mouse embryonic stem cells reveal that loss of PWWP2A/B leads to increases in histone acetylation predominantly at highly expressed genes, accompanied by decreases in Pol II elongation. Collectively, these findings suggest a role for PWWP2A/B in regulating transcription through the fine-tuning of histone acetylation dynamics at actively transcribed genes. | 30228260 |
| 2017-08-12 12:12:00 | Thus, PWWP2A is a novel H2A.Z-specific multivalent chromatin binder providing a surprising link between H2A.Z, chromosome segregation, and organ development. | 28645917 |
| Type | IDs |
|---|---|
| Synonymous | MST101 |
| Gene |
UniProtKB-ID:
PWP2A_HUMAN
UniprotKB:
Q96N64
UniParc:
UPI00001D7EEC,
UPI0000EE3692,
UPI0000EE3691
EMBL:
BC105110,
AC008706,
AK055921,
BC035076,
CH471062,
AB067522
Ensembl:
ENSG00000170234
KO:
hsa:114825
|
| Nucleutide sequences |
EMBL-CDS:
EAW61567.1,
BAB67828.1,
BAB71045.1,
AAH35076.2,
EAW61568.1,
AAI05111.1
Ensembl_TRS:
ENST00000456329,
ENST00000307063,
ENST00000523662
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000390462,
ENSP00000428143,
ENSP00000305151
RefSeq:
XP_005265869.1,
NP_001336663.1,
XP_024310122.1,
XP_024310121.1,
XP_016864501.1,
NP_001253964.1,
NP_001336664.1,
XP_005265868.1,
XP_011532726.1,
NP_001336661.1,
XP_016864500.1,
NP_443159.1,
NP_001124336.1,
XP_016864499.1,
NP_001336662.1
|
| Others |
UniRef100:
UniRef100_Q96N64
UniRef90:
UniRef90_Q96N64
UniRef50:
UniRef50_Q96N64
UniGene:
Hs.744960
CCDS:
CCDS47332.1,
CCDS58990.1,
CCDS47331.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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