| Type | Description |
|---|---|
| Definition | activin A receptor, type II-like 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-12 13:28:00 | Alk1 haploinsufficiency causes glomerular dysfunction and microalbuminuria in diabetic mice. | 32753679 |
| 2020-08-22 15:25:00 | The ALK-1/SMAD/ATOH8 axis attenuates hypoxic responses and protects against the development of pulmonary arterial hypertension. | 31719172 |
| 2019-07-13 11:40:00 | Loss of ALK1 function in endothelial cells results in increased activity of the PI3K pathway and vascular hyperplasia. | 29449337 |
| 2018-10-20 11:18:00 | our data show that in a tumor environment BMP9 and BMP10 play different roles and thus blocking their shared receptor ALK1 is maybe not appropriate. Indeed, BMP9, but not BMP10, acts as a quiescence factor on tumor growth, lung metastasis and vessel normalization. | 30165893 |
| 2018-09-01 11:50:00 | These studies identified pathways mediating LDLR-independent uptake of LDL may provide unique opportunities to block the initiation of LDL accumulation in the vessel wall or augment hepatic LDLR-dependent clearance of LDL. | 27869117 |
| Type | IDs |
|---|---|
| Synonymous | AI115505, AI427544, Acvrlk1, Alk1 |
| Gene |
UniProtKB-ID:
ACVL1_MOUSE
UniprotKB:
Q61288
UniParc:
UPI00000E83D2
EMBL:
CH466550,
AK160915,
L48015,
Z31664,
AK170870,
BC015083
Ensembl:
ENSMUSG00000000530
KO:
mmu:11482
|
| Nucleutide sequences |
EMBL-CDS:
AAH15083.1,
BAE36089.1,
EDL04061.1,
AAB03642.1,
BAE42083.1,
CAA83484.1,
EDL04063.1
Ensembl_TRS:
ENSMUST00000117984,
ENSMUST00000121718,
ENSMUST00000120028,
ENSMUST00000119063,
ENSMUST00000000542,
ENSMUST00000120754
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000112490,
ENSMUSP00000114027,
ENSMUSP00000113505,
ENSMUSP00000000542,
ENSMUSP00000113536,
ENSMUSP00000113297
RefSeq:
NP_001264187.1,
NP_001264188.1,
NP_001264186.1,
NP_033742.2,
NP_001264184.1
|
| Others |
UniRef100:
UniRef100_Q61288
UniRef90:
UniRef90_Q61288
UniRef50:
UniRef50_P37023
UniGene:
Mm.279542
CCDS:
CCDS37215.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员