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114815 SORCS1

114815

SORCS1

sortilin related VPS10 domain containing receptor 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition sortilin related VPS10 domain containing receptor 1

研究结论

Date Results Publications
2020-03-14 10:43:00 SorCS1 is epigenetically inactivated in a substantial fraction of colorectal cancers 31829024
2017-10-07 10:05:00 Here the authors have characterized SorCS1, SorCS2 and SorCS3 using biochemical methods and electron microscopy. They found that their purified extracellular domains co-exist in stable dimeric and monomeric populations. 28827148
2016-12-31 10:37:00 We report for the first time the relevance of SORCS1 polymorphisms for glycemic control and glucose stimulated insulin secretion in obese women with polycystic ovary syndrome. SORCS1 rs1416406 significantly influenced stimulated glucose plasma levels and increased glucose stimulated insulin secretion 27052493
2014-03-08 11:18:00 Data identified associations between single nucleotide polymorphisms in SORCS1 and renal function in large cohorts of European and African ancestry. 23780848
2014-03-01 11:50:00 The propeptide region of sorCS1 contains two separate sites for binding to sortilin. One of these sites is removed from human sorCS1 during processing. 24128306

名称对应

Type IDs
Synonymous hSorCS
Gene
UniProtKB-ID: SORC1_HUMAN, E6Y3G0_HUMAN, B3KVZ0_HUMAN, E6Y3F9_HUMAN, B3KWN9_HUMAN, A8K182_HUMAN
UniprotKB: Q8WY21, E6Y3G0, B3KVZ0, E6Y3F9, B3KWN9, A8K182
UniParc: UPI000036671B, UPI0001F3463A, UPI0000D4766D, UPI00001AE866, UPI000000D819, UPI000000D81A, UPI0001F3463B, UPI0000EE3C2E, UPI00004A248B
EMBL: AL356255, AL356308, AL357333, EU281344, AK289797, BC131597, AL160010, AK123752, AL133395, EU281343, AK125464, CH471066, AY099453, AY099452, AB209142, AF284756
Ensembl: ENSG00000108018
KO: hsa:114815
Nucleutide sequences
EMBL-CDS: AAM43812.1, AAM43811.1, AAI31598.1, BAD92379.1, EAW49583.1, AAL56667.1, ABZ89712.1, BAG53952.1, ABZ89711.1, BAG54201.1, BAF82486.1, EAW49586.1
Gene_ORFName: hCG_1811156
Ensembl_TRS: ENST00000263054
Protein sequencees
Ensembl_PRO: ENSP00000263054
RefSeq: XP_011537501.1, XP_016871105.1, NP_001193498.1, XP_016871104.1, XP_016871106.1, XP_016871107.1, NP_001013049.1, XP_011537503.1, NP_443150.3, NP_001193500.1, NP_001193501.1, NP_001193499.1, NP_001374485.1
Others
UniRef100: UniRef100_Q8WY21, UniRef100_A8K182, UniRef100_Q8WY21-2, UniRef100_E6Y3G0, UniRef100_E6Y3F9, UniRef100_B3KWN9
UniRef90: UniRef90_Q8WY21, UniRef90_Q8WY21-2
UniRef50: UniRef50_Q8WY21
UniGene: Hs.591915
CCDS: CCDS7559.1

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