| Type | Description |
|---|---|
| Definition | activin receptor IIA |
| Date | Results | Publications |
|---|---|---|
| 2020-12-19 13:40:00 | Murine FSH Production Depends on the Activin Type II Receptors ACVR2A and ACVR2B. | 32270195 |
| 2018-12-22 10:47:00 | Activation of ActRIIA signaling during early chronic kidney disease contributes to the CKD-MBD components of osteodystrophy and cardiovascular disease and to renal fibrosis. | 28843411 |
| 2018-09-29 10:16:00 | blocking activin/ACVR2A impaired the potency of hepatic stellate cells to produce collagens in response to IL17s. | 29620144 |
| 2017-10-28 11:56:00 | Anti-ActRII blockade is an effective intervention against cancer cachexia providing benefit even in the presence of anti-cancer therapies. | 27462398 |
| 2017-09-09 12:29:00 | Data, including data from studies using transgenic mice, suggest that osteoblasts deficient in Acvr2A exhibit un-characteristic features; osteoclasts deficient in Acvr2A or Acvr2B or both appear normal. Acvr2A-deficient mice exhibit significantly increased femoral trabecular bone volume at 6 weeks of age; Acvr2B-deficient mice exhibit no significant change in any bone parameter. | 28659341 |
| Type | IDs |
|---|---|
| Synonymous | ActrIIa, Acvr2, TactrII |
| Gene |
UniProtKB-ID:
AVR2A_MOUSE,
A2AI38_MOUSE,
Q8BRV4_MOUSE
UniprotKB:
P27038,
A2AI38,
Q8BRV4
UniParc:
UPI0000027905,
UPI00000EAD8A
EMBL:
M65287,
AK041246,
BC138823
Ensembl:
ENSMUSG00000052155
KO:
mmu:11480
|
| Nucleutide sequences |
EMBL-CDS:
AAA37171.1,
AAI38824.1,
BAC30877.1
Ensembl_TRS:
ENSMUST00000063886
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000067305
RefSeq:
NP_031422.3,
XP_006497686.1
|
| Others |
UniRef100:
UniRef100_P27038,
UniRef100_Q8BRV4
UniRef90:
UniRef90_P27038
UniRef50:
UniRef50_P27040-2
UniGene:
Mm.314338
CCDS:
CCDS16021.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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