| Type | Description |
|---|---|
| Definition | caspase recruitment domain family member 16 |
| Date | Results | Publications |
|---|---|---|
| 2016-09-03 10:55:00 | Expression of NOX4/p22(phox) as well as production is enhanced by IL-1beta. On the other hand, the use of NOX4 inhibitors decreased IL-1beta-induced collagenase synthesis by chondrocytes. | 26521743 |
| 2010-09-15 22:06:00 | Observational study of gene-disease association. (HuGE Navigator) | 19913121 |
| 2010-09-15 22:06:00 | Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) | 20628086 |
| 2010-01-21 00:00:00 | Caspase-1-mediated cell death is regulated, at least in part, by the balance of Rip2 and Cop; alterations of this balance may contribute to aberrant caspase-1-mediated pathogenesis in Huntington's disease. | 16354923 |
| 2010-01-21 00:00:00 | Cop inhibition of cell death, at least to a certain extent, results from its interference with the activation of caspase-1 and caspase-4. | 16920334 |
| Type | IDs |
|---|---|
| Synonymous | COP, COP1, PSEUDO-ICE |
| Gene |
UniProtKB-ID:
CAR16_HUMAN
UniprotKB:
Q5EG05
UniParc:
UPI00004C9CE7,
UPI0000046175
EMBL:
BC117480,
BC117478,
AK311902,
CH471065,
AF367017,
AY885669
Ensembl:
ENSG00000204397
KO:
hsa:114769
|
| Nucleutide sequences |
EMBL-CDS:
AAK71682.1,
AAI17479.1,
AAI17481.1,
EAW67062.1,
BAG34843.1,
AAW78563.1
Ensembl_TRS:
ENST00000375706,
ENST00000375704
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000364858,
ENSP00000364856
RefSeq:
NP_443121.1,
XP_011540885.1,
NP_001017534.1
|
| Others |
UniRef100:
UniRef100_Q5EG05
UniRef90:
UniRef90_Q5EG05
UniRef50:
UniRef50_Q5EG05
UniGene:
Hs.348365
CCDS:
CCDS41705.1,
CCDS31661.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 26521743 |
Osteoarthr. Cartil. F Rousset , F Hazane-Puch , C Pinosa , M V C Nguyen , L Grange , A Soldini , B Rubens-Duval , C Dupuy , F Morel , B Lardy |
2015-11-01 | - |
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 20479761 |
Mol Psychiatry R C Shelton , J Claiborne , M Sidoryk-Wegrzynowicz , R Reddy , M Aschner , D A Lewis , K Mirnics |
2011-07-01 | - |
| 20628086 |
Diabetes Care Swneke D Bailey , Changchun Xie , Ron Do , Alexandre Montpetit , Rafael Diaz , Viswanathan Mohan , Bernard Keavney , Salim Yusuf , Hertzel C Gerstein , James C Engert , Sonia Anand , DREAM investigators |
2010-10-01 | - |
| 19913121 |
Am. J. Hum. Genet. Philippa J Talmud , Fotios Drenos , Sonia Shah , Tina Shah , Jutta Palmen , Claudio Verzilli , Tom R Gaunt , Jacky Pallas , Ruth Lovering , Kawah Li , Juan Pablo Casas , Reecha Sofat , Meena Kumari , Santiago Rodriguez , Toby Johnson , Stephen J Newhouse , Anna Dominiczak , Nilesh J Samani , Mark Caulfield , Peter Sever , Alice Stanton , Denis C Shields , Sandosh Padmanabhan , Olle Melander , Claire Hastie , Christian Delles , Shah Ebrahim , Michael G Marmot , George Davey Smith , Debbie A Lawlor , Patricia B Munroe , Ian N Day , Mika Kivimaki , John Whittaker , Steve E Humphries , Aroon D Hingorani , ASCOT investigators , NORDIL investigators , BRIGHT Consortium |
2009-11-01 | - |
| 18187620 |
Identification of host proteins required for HIV infection through a functional genomic screen. Science Abraham L Brass , Derek M Dykxhoorn , Yair Benita , Nan Yan , Alan Engelman , Ramnik J Xavier , Judy Lieberman , Stephen J Elledge |
2008-02-15 |
gag,
gag-pol,
vif,
vpr,
tat,
rev,
vpu,
env,
nef,
MED6,
PIGK,
HUWE1,
PDIA6,
MPHOSPH6,
ADAM10,
RABEPK,
RRAGB,
ATG7,
ARPC1A,
POLR3F,
LEFTY1,
PNRC1,
TMED2,
PRDM7,
POLR3A,
ERI2,
SLC46A1,
SFT2D1,
GABARAPL2,
CARD16,
PKD1L2,
XKR4,
AGAP2,
AP2M1,
CLN3,
CLNS1A,
ERP27,
ANKRD9,
ZNF720,
RPTN,
ARHGEF19,
ZNF831,
C4orf33,
SOWAHA,
C9orf131,
RIMS4,
FAM76B,
ZNF785,
LYPD4,
PM20D1,
IQUB,
ZNF791,
DDOST,
DDX3X,
DMXL1,
DDX10,
TIMM8A,
DDX53,
EDNRA,
AGO3,
EGF,
EGFR,
CRTC2,
EPS8,
ERCC3,
AKT1,
AKT2,
ETF1,
DOK6,
C6orf1,
LNX2,
FHL3,
COG2,
TRAPPC8,
ANKRD6,
BAHD1,
FBXO21,
WDTC1,
FLII,
SEPT8,
MDN1,
OTUD3,
SCFD1,
NUP160,
FBXW11,
ARHGEF12,
FNTA,
PIP5K1C,
PHF3,
ETHE1,
TNPO3,
KLHDC2,
MKRN2,
COG4,
TRIM58,
INTS7,
SPATS2L,
GAPVD1,
RSL1D1
|
| 16920334 |
Protective role of Cop in Rip2/caspase-1/caspase-4-mediated HeLa cell death. Biochim. Biophys. Acta Xin Wang , Malini Narayanan , Jean-Marie Bruey , Dorotea Rigamonti , Elena Cattaneo , John C Reed , Robert M Friedlander |
2006-08-01 |
Casp1,
CARD16,
CASP1,
CASP4,
RIPK2
|
| 16354923 |
J. Neurosci. Xin Wang , Hongyan Wang , Bryan E Figueroa , Wen-Hua Zhang , Chunfeng Huo , Yingjun Guan , Yu Zhang , Jean-Marie Bruey , John C Reed , Robert M Friedlander |
2005-12-14 | - |
| 15383541 |
INCA, a novel human caspase recruitment domain protein that inhibits interleukin-1beta generation. J Biol Chem Mohamed Lamkanfi , Geertrui Denecker , Michael Kalai , Kathleen D'hondt , Ann Meeus , Wim Declercq , Xavier Saelens , Peter Vandenabeele |
2004-12-10 | - |
| 14702039 |
Complete sequencing and characterization of 21,243 full-length human cDNAs. Nat. Genet. Toshio Ota , Yutaka Suzuki , Tetsuo Nishikawa , Tetsuji Otsuki , Tomoyasu Sugiyama , Ryotaro Irie , Ai Wakamatsu , Koji Hayashi , Hiroyuki Sato , Keiichi Nagai , Kouichi Kimura , Hiroshi Makita , Mitsuo Sekine , Masaya Obayashi , Tatsunari Nishi , Toshikazu Shibahara , Toshihiro Tanaka , Shizuko Ishii , Jun-ichi Yamamoto , Kaoru Saito , Yuri Kawai , Yuko Isono , Yoshitaka Nakamura , Kenji Nagahari , Katsuhiko Murakami , Tomohiro Yasuda , Takao Iwayanagi , Masako Wagatsuma , Akiko Shiratori , Hiroaki Sudo , Takehiko Hosoiri , Yoshiko Kaku , Hiroyo Kodaira , Hiroshi Kondo , Masanori Sugawara , Makiko Takahashi , Katsuhiro Kanda , Takahide Yokoi , Takako Furuya , Emiko Kikkawa , Yuhi Omura , Kumi Abe , Kumiko Kamihara , Naoko Katsuta , Kazuomi Sato , Machiko Tanikawa , Makoto Yamazaki , Ken Ninomiya , Tadashi Ishibashi , Hiromichi Yamashita , Katsuji Murakawa , Kiyoshi Fujimori , Hiroyuki Tanai , Manabu Kimata , Motoji Watanabe , Susumu Hiraoka , Yoshiyuki Chiba , Shinichi Ishida , Yukio Ono , Sumiyo Takiguchi , Susumu Watanabe , Makoto Yosida , Tomoko Hotuta , Junko Kusano , Keiichi Kanehori , Asako Takahashi-Fujii , Hiroto Hara , Tomo-o Tanase , Yoshiko Nomura , Sakae Togiya , Fukuyo Komai , Reiko Hara , Kazuha Takeuchi , Miho Arita , Nobuyuki Imose , Kaoru Musashino , Hisatsugu Yuuki , Atsushi Oshima , Naokazu Sasaki , Satoshi Aotsuka , Yoko Yoshikawa , Hiroshi Matsunawa , Tatsuo Ichihara , Namiko Shiohata , Sanae Sano , Shogo Moriya , Hiroko Momiyama , Noriko Satoh , Sachiko Takami , Yuko Terashima , Osamu Suzuki , Satoshi Nakagawa , Akihiro Senoh , Hiroshi Mizoguchi , Yoshihiro Goto , Fumio Shimizu , Hirokazu Wakebe , Haretsugu Hishigaki , Takeshi Watanabe , Akio Sugiyama , Makoto Takemoto , Bunsei Kawakami , Masaaki Yamazaki , Koji Watanabe , Ayako Kumagai , Shoko Itakura , Yasuhito Fukuzumi , Yoshifumi Fujimori , Megumi Komiyama , Hiroyuki Tashiro , Akira Tanigami , Tsutomu Fujiwara , Toshihide Ono , Katsue Yamada , Yuka Fujii , Kouichi Ozaki , Maasa Hirao , Yoshihiro Ohmori , Ayako Kawabata , Takeshi Hikiji , Naoko Kobatake , Hiromi Inagaki , Yasuko Ikema , Sachiko Okamoto , Rie Okitani , Takuma Kawakami , Saori Noguchi , Tomoko Itoh , Keiko Shigeta , Tadashi Senba , Kyoka Matsumura , Yoshie Nakajima , Takae Mizuno , Misato Morinaga , Masahide Sasaki , Takushi Togashi , Masaaki Oyama , Hiroko Hata , Manabu Watanabe , Takami Komatsu , Junko Mizushima-Sugano , Tadashi Satoh , Yuko Shirai , Yukiko Takahashi , Kiyomi Nakagawa , Koji Okumura , Takahiro Nagase , Nobuo Nomura , Hisashi Kikuchi , Yasuhiko Masuho , Riu Yamashita , Kenta Nakai , Tetsushi Yada , Yusuke Nakamura , Osamu Ohara , Takao Isogai , Sumio Sugano |
2004-01-01 |
Slc9a8,
Nefm,
Hfe2,
AKT3,
ZBTB11-AS1,
LOC100034248,
PDZK1P1,
DDTL,
LOC100049716,
ACOT8,
GNPDA1,
ZBTB33,
GTF2IP4,
POM121C,
ZSCAN30,
SRA1,
SNORD123,
UCKL1-AS1,
ZGLP1,
LOC100125918,
LINC00322,
LOC100127940,
HECW1-IT1,
LOC100127955,
LOC100127972,
LOC100127974,
FAM229A,
LOC100128076,
STAU2-AS1,
LOC100128164,
TMPO-AS1,
LOC100128219,
LOC100128239,
LOC100128253,
TNK2-AS1,
DNM1P35,
LOC100128288,
DLG5-AS1,
LOC100128310,
TRAPPC3L,
FAM83H-AS1,
LOC100128361,
LOC100128364,
FAM225B,
LOC100128386,
LOC100128398,
ASTN2-AS1,
C1orf132,
MYHAS,
LOC100128651,
LINC00476,
SRRM2-AS1,
GPR158-AS1,
LINC01165,
VPS9D1-AS1,
FAM66B,
GATA6-AS1,
LINC01310,
LOC100128979,
LOC100128988,
LOC100129034,
SEMA3F-AS1,
UNQ6494,
LOC100129115,
KHDC1L,
LOC100129175,
MATN1-AS1,
SLC39A12-AS1,
LOC100129297,
LOC100129312,
LINC00484,
LOC100129397,
LOC100129406,
DDC-AS1,
LOC100129434,
LOC100129447,
LOC100129455,
LYRM4-AS1,
ZNF37BP,
LOC100129516,
LOC100129518,
LOC100129540,
LOC100129572,
FAM47E,
LOC100129620,
LOC100129648,
C9orf173-AS1,
LOC100129775,
SLC25A21-AS1,
PCOLCE-AS1,
SCOC-AS1,
LOC100129884,
LOC100129894,
LOC100129917,
LOC100129935,
LOC100130078,
LOC100130111,
MAPT-IT1,
MIR124-2HG
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员