| Type | Description |
|---|---|
| Definition | sprouty protein with EVH-1 domain 1, related sequence |
| Date | Results | Publications |
|---|---|---|
| 2020-07-25 12:43:00 | Using established mice lines deficient for either or both Spred 1 and Spred 2, we demonstrate their role in regulating lens development by negatively regulating ERK1/2 activity. | 31923414 |
| 2019-10-12 11:02:00 | Exercise training increased endothelial progenitor cells function in experimental myocardial infarction mice and miR-126 expression, while Spred1 expression was significantly down-regulated. | 29265525 |
| 2019-09-07 12:30:00 | The Spred1 deficiency mitigates hematopoietic stem cell (HSC) failure induced by infection mimetics and prolongs HSC lifespan, but it does not initiate leukemogenesis due to compensatory upregulation of Spred2. | 29706577 |
| 2016-03-05 11:03:00 | Cosuppression of Sprouty and Sprouty-related negative regulators of FGF signalling in prostate cancer | 26075267 |
| 2016-01-02 10:17:00 | SPREDs promote self-renewal and inhibit mesodermal differentiation of murine ES cells by selective suppression of the ERK/MAPK signaling pathway in pluripotent cells | 25690936 |
| Type | IDs |
|---|---|
| Synonymous | 5730461F13Rik, AL024345, AW047647 |
| Gene |
UniProtKB-ID:
SPRE1_MOUSE
UniprotKB:
Q924S8
UniParc:
UPI0000216E15,
UPI0000029039
EMBL:
AL928959,
BC057874,
BC079606,
AL807741,
AB063495,
AK155065
Ensembl:
ENSMUSG00000027351
KO:
mmu:114715
|
| Nucleutide sequences |
EMBL-CDS:
BAE33024.1,
AAH79606.1,
AAH57874.1,
BAB62848.1
Ensembl_TRS:
ENSMUST00000028829,
ENSMUST00000110901
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000028829,
ENSMUSP00000106526
RefSeq:
NP_001264185.1,
NP_277059.1
|
| Others |
UniRef100:
UniRef100_Q924S8
UniRef90:
UniRef90_Q924S8
UniRef50:
UniRef50_Q7Z699
UniGene:
Mm.245890,
Mm.392720,
Mm.392726,
Mm.397626
CCDS:
CCDS16570.1,
CCDS71115.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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