| Type | Description |
|---|---|
| Definition | RAD51 paralog C |
| Date | Results | Publications |
|---|---|---|
| 2020-04-04 11:43:00 | we demonstrate that miR-222 up-regulation, directly regulates Rad51c expression negatively, and impairs homologous recombination of double-strand break DNA repair during the initiation stage of cell transformation. | 31923208 |
| 2017-09-02 13:39:00 | Similar to other BC models, Rad51c/p53 double-mutant mouse mammary tumors also reveal a propensity for genomic instability, but lack the focal amplification of the Met locus or distinct mutational signatures reported for other HR genes | 26820992 |
| 2015-03-21 10:35:00 | a critical synergy between Rad51c and Trp53 in tumour progression and provide a predictable in vivo model system for studying mechanisms of Rad51c-mediated carcinogenesis | 25270124 |
| 2010-08-23 11:28:00 | These results imply that adequate expression of Rad51C in mammalian cells is essential for maintaining genomic stability and sister chromatid cohesion to prevent malignant transformation. | 20471405 |
| 2010-01-21 00:00:00 | DNA replication licensing factor MCM2 and DNA mismatch repair (MMR) protein MSH2 were confirmed to be present in co-precipitations with MmRAD51C. | 19658102 |
| Type | IDs |
|---|---|
| Synonymous | R51H3, Rad51l2 |
| Gene |
UniProtKB-ID:
RA51C_MOUSE
UniprotKB:
Q924H5
UniParc:
UPI000024F76F,
UPI0000021039
EMBL:
CU406969,
BC141034,
CH466556,
AL669902,
AF324883,
CU406989,
AK076551,
AL596130,
BC090648
Ensembl:
ENSMUSG00000007646
KO:
mmu:114714
|
| Nucleutide sequences |
EMBL-CDS:
CAI35963.1,
AAI41035.1,
BAC36388.1,
CAI24487.1,
AAH90648.1,
CAI24486.1,
CAQ52016.1,
CAQ51530.1,
AAK58420.1,
EDL15814.1,
CAQ51531.1,
CAI35964.1,
CAQ52015.1
Ensembl_TRS:
ENSMUST00000067692,
ENSMUST00000007790
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000064079,
ENSMUSP00000007790
RefSeq:
XP_036012127.1,
XP_036012128.1,
NP_444499.1,
NP_001278369.1
|
| Others |
UniRef100:
UniRef100_Q924H5
UniRef90:
UniRef90_Q924H5
UniRef50:
UniRef50_Q924H5
UniGene:
Mm.37376
CCDS:
CCDS25212.1,
CCDS79013.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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