| Type | Description |
|---|---|
| Definition | bromodomain, testis-specific |
| Date | Results | Publications |
|---|---|---|
| 2018-07-14 10:35:00 | BRDT controls the global chromatin organization and histone modifications of the chromatin attached to the synaptonemal complex. BRDT role in the silencing of sex chromosomes and crossover formation in male meiosis. | 29513658 |
| 2017-06-03 10:53:00 | Our results suggest that in addition to its critical role in the spermatogenesis process, the BRDT protein is also responsible for scheduling male puberty by regulation of the pituitary-gonad axis. | 26994494 |
| 2013-01-12 10:49:00 | It was shown that Brdt is a unique and essential regulator of male germ cell differentiation, first by driving a specific spermatogenic gene expression program and then by controling the tight packaging of the male genome. | 22922464 |
| 2012-04-28 10:59:00 | The N terminus of Brdt is involved in the recognition of Smarce1 as well as in the reorganization of hyperacetylated round spermatid chromatin. | 22215678 |
| 2012-01-28 12:16:00 | the first bromodomain of Brdt is critical in the formation and/or maintenance of an intact chromocenter and implicate this structure in proper remodeling of the chromatin architecture of the sperm head. | 22020252 |
| Type | IDs |
|---|---|
| Synonymous | 7420412D09Rik, Brd6, Fsrg3 |
| Gene |
UniProtKB-ID:
BRDT_MOUSE,
Q8BNZ8_MOUSE
UniprotKB:
Q91Y44,
Q8BNZ8
UniParc:
UPI000024DEA7,
UPI00001F331B,
UPI00000EB13B
EMBL:
AC126598,
AK078663,
AB208640,
AF358660,
CH466529
Ensembl:
ENSMUSG00000029279
KO:
mmu:114642
|
| Nucleutide sequences |
EMBL-CDS:
EDL20168.1,
BAD91553.1,
AAK50736.1,
BAC37352.1
Ensembl_TRS:
ENSMUST00000031215,
ENSMUST00000112677
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000108297,
ENSMUSP00000031215
RefSeq:
NP_001073342.1,
XP_030109920.1,
XP_030109918.1,
NP_473395.2,
XP_011247700.1,
XP_006534792.1,
XP_030109919.1,
XP_006534791.1,
XP_030109921.1,
XP_006534793.1
|
| Others |
UniRef100:
UniRef100_Q91Y44
UniRef90:
UniRef90_Q91Y44
UniRef50:
UniRef50_Q58F21
UniGene:
Mm.182836
CCDS:
CCDS19500.1,
CCDS39197.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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