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11464 Actc1

11464

Actc1

actin, alpha, cardiac muscle 1

protein-coding

Mus musculus

基因描述

Type Description
Definition actin, alpha, cardiac muscle 1

研究结论

Date Results Publications
2017-12-23 12:29:00 This study provides novel insights into the complex genetic regulation of Actc1 expression in early adult skeletal muscles. 28847732
2017-11-18 12:50:00 Analogous to the findings in human skeletal muscle, Actc1 expression in mouse gastrocnemius muscle increased after testosterone deprivation in orchidectomized mice compared with sham controls 28756295
2016-04-16 11:58:00 ACTC E361G mutation uncouples the relationship between Ca(2+) sensitivity and troponin I phosphorylation, predisposing the heart to dilated cardiomyopathy under conditions of chronic stress. 26432839
2014-05-03 11:56:00 results demonstrate that in ACTC(Co)/KO myofibres, the presence of cardiac alpha-actin instead of skeletal muscle alpha-actin alters actin conformational changes upon activation; this later finely modulates the strain of individual actomyosin interactions and overall lowers myofibre force production 23784376
2013-11-16 10:04:00 Data indicate that the tri-helix bundle is important to the regulatory role of cMyBP-C, likely through actin-binding interactions. 23782699

名称对应

Type IDs
Synonymous Actc-1
Gene
UniProtKB-ID: ACTC_MOUSE, Q497E4_MOUSE
UniprotKB: P68033, Q497E4
UniParc: UPI0000003F15
EMBL: AK168661, BC100600, M15501, AK014303, AK169165, BC062138, AK169161, AK168637
Ensembl: ENSMUSG00000068614
KO: mmu:11464
Nucleutide sequences
EMBL-CDS: AAH62138.1, BAB29258.1, AAA37167.1, BAE40940.1, AAI00601.1, BAE40515.1, BAE40944.1, BAE40497.1
Ensembl_TRS: ENSMUST00000090269
Protein sequencees
Ensembl_PRO: ENSMUSP00000087736
RefSeq: NP_033738.1
Others
UniRef100: UniRef100_P68032
UniRef90: UniRef90_P68032
UniRef50: UniRef50_P68032
UniGene: Mm.686
CCDS: CCDS16564.1

全选

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研究热度

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