| Type | Description |
|---|---|
| Definition | TIR domain containing adaptor protein |
| Date | Results | Publications |
|---|---|---|
| 2020-06-13 12:49:00 | role of Mal signal in the maintenance of DEC205(+) dendritic cell immune tolerogenic function | 31196568 |
| 2020-06-06 11:24:00 | Results found no association between TIRAP S180L variant and disease severity among human active Tuberculosis (TB) cases. | 31678649 |
| 2020-05-09 12:26:00 | The identification of an inherited TIRAP variant provides evidence for a novel link between genetic alterations affecting the NF-kappaB pathway and lymphomagenesis. | 30381301 |
| 2020-05-02 10:51:00 | Lung cancer cells express low Mal (TIRAP) levels that contributes to FasL mRNA decay through impairing TDP-43 expression.Mal induces TDP-43 expression to stabilize FasL expression. | 31978067 |
| 2020-02-15 12:54:00 | IRAK1, TLR4, and TIRAP gene variants have an effect on expression of TNF-alpha, IL-6, MCP-1, and IL-1beta in type 2 diabetes and insulin resistance | 31222667 |
| Type | IDs |
|---|---|
| Synonymous | BACTS1, Mal, MyD88-2, wyatt |
| Gene |
UniProtKB-ID:
TIRAP_HUMAN,
A0A024R3M4_HUMAN
UniprotKB:
P58753,
A0A024R3M4
UniParc:
UPI0000167B7D,
UPI0000136FBA,
UPI0000688156
EMBL:
AF406652,
AB446477,
BC032474,
AY282416,
AY576786,
AF378129,
AK313147,
AF410783,
AP001318,
AY576787,
CH471065,
AY576785,
AK124298
Ensembl:
ENSG00000150455
KO:
hsa:114609
|
| Nucleutide sequences |
EMBL-CDS:
BAG54027.1,
BAG55254.1,
AAL05036.1,
BAG35965.1,
EAW67689.1,
AAP31973.1,
AAT90418.1,
AAL05627.1,
EAW67687.1,
AAL01160.1,
AAT90417.1,
AAT90419.1,
AAH32474.1,
EAW67688.1
Gene_ORFName:
hCG_2032769
Ensembl_TRS:
ENST00000392678,
ENST00000392680,
ENST00000479770,
ENST00000392679
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000376445,
ENSP00000376446,
ENSP00000436967,
ENSP00000376447
RefSeq:
NP_683708.1,
NP_001034750.1,
NP_001305705.1,
NP_001305706.1
|
| Others |
UniRef100:
UniRef100_P58753
UniRef90:
UniRef90_P58753
UniRef50:
UniRef50_P58753
UniGene:
Hs.537126
CCDS:
CCDS41731.1,
CCDS8472.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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