| Type | Description |
|---|---|
| Definition | chloride intracellular channel 1 |
| Date | Results | Publications |
|---|---|---|
| 2017-12-09 11:44:00 | Results indicate CLICs (CLIC1, CLIC4 and CLIC5)-dependent chloride efflux as an essential and proximal upstream event for NLRP3 activation. | 28779175 |
| 2017-12-09 10:33:00 | We conclude that the role of CLIC1 in macrophage superoxide production is to support redistribution of NADPH oxidase to the plasma membrane, and not through major effects on ERM cytoskeleton or by acting as a plasma membrane chloride channel. | 28275112 |
| 2017-08-12 10:16:00 | Data, including data from studies in primary cells from knockout mice, suggest Clic1 and Clic4 participate in signaling interleukin 1beta secretion and in activation of Nlrp3 inflammasomes; in LPS macrophage activation, Clic1 and Clic4 are translocated to nucleus/cell membranes. (Clic1 = chloride intracellular channel 1; Clic4 = chloride intracellular channel 4, mitochondrial; Nlrp3 = NLR family pyrin domain containing 3) | 28576828 |
| 2017-07-01 10:59:00 | This study demonstrates for the first time that CLIC1 is overexpressed during AS development both in vitro and in vivo and can regulate the accumulation of inflammatory cytokines and production of oxidative stress. | 27861612 |
| 2016-04-02 10:50:00 | Results indicate that CLIC1 is an important contributor to tumor invasion, metastasis, and angiogenesis. | 25205595 |
| Type | IDs |
|---|---|
| Synonymous | Clcp, G6 |
| Gene |
UniProtKB-ID:
CLIC1_MOUSE,
Q542F1_MOUSE
UniprotKB:
Q9Z1Q5,
Q542F1
UniParc:
UPI000000186E
EMBL:
AF109905,
AK150382,
AK150611,
BC004658,
AK168262,
AK153509,
AK088809
Ensembl:
ENSMUSG00000007041
KO:
mmu:114584
|
| Nucleutide sequences |
EMBL-CDS:
AAC84155.1,
AAH04658.1,
BAE40210.1,
BAE32054.1,
BAE29513.1,
BAC40585.1,
BAE29702.1
Ensembl_TRS:
ENSMUST00000007257
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000007257
RefSeq:
NP_254279.1
|
| Others |
UniRef100:
UniRef100_Q9Z1Q5
UniRef90:
UniRef90_O00299
UniRef50:
UniRef50_O00299
UniGene:
Mm.29524
CCDS:
CCDS28675.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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