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114516 Glra3

114516

Glra3

glycine receptor, alpha 3

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition glycine receptor, alpha 3

研究结论

Date Results Publications
2017-05-13 13:43:00 data show that the current-voltage relationships of homomeric channels formed by the alpha2 or alpha3 subunits change upon receptor desensitization from a linear to an inwardly rectifying shape, in contrast to their heteromeric counterparts. 27382060
2014-02-01 12:19:00 The kinetic properties of the alpha3 rat glycine receptor make it suitable for mediating fast synaptic inhibition. 23613537
2012-01-14 11:23:00 Alteration in glycine receptor subunit expression starts as early as 6 hours after spinal cord injury. 20733588
2010-01-21 00:00:00 the long (L) splice variant of GlyR alpha3 predominates in the brain of rodents. In primary hippocampal neurons GlyR alpha3L clusters also preferred glutamatergic nerve endings while alpha3K was mainly in a diffuse state. 19723286
2010-01-21 00:00:00 GlyR alpha3(P185L), a result of cytidine 554 deamination, confers high glycine sensitivity (EC50 approximately 5 microM) to neurons and thereby promotes the generation of sustained chloride conductances associated with tonic inhibition 15895087

名称对应

Type IDs
Gene
UniProtKB-ID: Q99JC9_RAT
UniprotKB: Q99JC9
UniParc: UPI00000E7252
EMBL: AJ310838
KO: rno:114516
Nucleutide sequences
EMBL-CDS: CAC35982.1
Protein sequencees
RefSeq: NP_446176.3
Others
UniRef100: UniRef100_Q99JC9
UniRef90: UniRef90_O75311
UniRef50: UniRef50_O75311
UniGene: Rn.10038

全选

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研究热度

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