| Type | Description |
|---|---|
| Definition | valyl-tRNA synthetase |
| Date | Results | Publications |
|---|---|---|
| 2019-04-13 11:08:00 | Authors report an allelic series consisting of seven novel and two previously reported biallelic variants in valyl-tRNA synthetase (VARS) in ten patients with a developmental encephalopathy with microcephaly, often associated with early-onset epilepsy. | 30755616 |
| Type | IDs |
|---|---|
| Synonymous | CHUNP6879, im:7137378, vars1, vars2, wu:fb07a11, wu:fb07d10 |
| Gene |
UniProtKB-ID:
F1Q740_DANRE
UniprotKB:
F1Q740
UniParc:
UPI00020277A2
EMBL:
CU929328
Ensembl:
ENSDARG00000044575
KO:
dre:114427
|
| Nucleutide sequences |
Ensembl_TRS:
ENSDART00000173132
|
| Protein sequencees |
Ensembl_PRO:
ENSDARP00000142328
RefSeq:
NP_001298275.1
|
| Others |
UniRef100:
UniRef100_F1Q740
UniRef90:
UniRef90_F1Q740
UniRef50:
UniRef50_P49696
UniGene:
Dr.1481
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 30755616 |
Nat Commun Aleksandra Siekierska , Hannah Stamberger , Tine Deconinck , Stephanie N Oprescu , Michèle Partoens , Yifan Zhang , Jo Sourbron , Elias Adriaenssens , Patrick Mullen , Patrick Wiencek , Katia Hardies , Jeong-Soo Lee , Hoi-Khoanh Giong , Felix Distelmaier , Orly Elpeleg , Katherine L Helbig , Joseph Hersh , Sedat Isikay , Elizabeth Jordan , Ender Karaca , Angela Kecskes , James R Lupski , Reka Kovacs-Nagy , Patrick May , Vinodh Narayanan , Manuela Pendziwiat , Keri Ramsey , Sampathkumar Rangasamy , Deepali N Shinde , Ronen Spiegel , Vincent Timmerman , Sarah von Spiczak , Ingo Helbig , C4RCD Research Group , AR working group of the EuroEPINOMICS RES Consortium , Sarah Weckhuysen , Christopher Francklyn , Anthony Antonellis , Peter de Witte , Peter De Jonghe |
2019-02-12 | - |
| 28252024 |
Evolution of complexity in the zebrafish synapse proteome. Nat Commun Ãlex Bayés , Mark O Collins , Rita Reig-Viader , Gemma Gou , David Goulding , Abril Izquierdo , Jyoti S Choudhary , Richard D Emes , Seth G N Grant |
2017-03-02 | - |
| 28934368 |
A single Danio rerio hars gene encodes both cytoplasmic and mitochondrial histidyl-tRNA synthetases. PLoS One Ashley L Waldron , Sara Helms Cahan , Christopher S Francklyn , Alicia M Ebert |
2017-01-01 | - |
| 27402763 |
p53-Dependent DNA damage response sensitive to editing-defective tRNA synthetase in zebrafish. Proc. Natl. Acad. Sci. U.S.A. Youngzee Song , Yi Shi , Tristan M Carland , Shanshan Lian , Tomoyuki Sasaki , Nicholas J Schork , Steven R Head , Shuji Kishi , Paul Schimmel |
2016-07-26 | - |
| 26469318 |
RFX transcription factors are essential for hearing in mice. Nat Commun Ran Elkon , Beatrice Milon , Laura Morrison , Manan Shah , Sarath Vijayakumar , Manoj Racherla , Carmen C Leitch , Lorna Silipino , Shadan Hadi , Michèle Weiss-Gayet , Emmanuèle Barras , Christoph D Schmid , Aouatef Ait-Lounis , Ashley Barnes , Yang Song , David J Eisenman , Efrat Eliyahu , Gregory I Frolenkov , Scott E Strome , Bénédicte Durand , Norann A Zaghloul , Sherri M Jones , Walter Reith , Ronna Hertzano |
2015-10-15 | - |
| 25267534 |
Gene Li Ren , Xing-Jun Tan , Ya-Feng Xiong , Kang Xu , Yi Zhou , Huan Zhong , Yun Liu , Yun-Han Hong , Shao-Jun Liu |
2014-12-01 |
zfyve21,
il6r,
ncoa6,
znf654,
phf13,
ndufv3,
vars,
invs,
gata4,
cfb,
igf2a,
cd63,
nol11,
alcamb,
zc2hc1a,
brdt,
ndufa11,
tnfrsf1a,
c1qc,
usp4,
tbl3,
acp2,
poli,
fitm2,
mrpl1,
arhgef28,
si:ch211-207d6.2,
ppp1r26,
ston2,
rnaseka,
npdc1a,
cbx8b
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 16448862 |
Gene Expr. Patterns Alexandra Tallafuss , Laura A Hale , Yi-Lin Yan , Leana Dudley , Judith S Eisen , John H Postlethwait |
2006-06-01 |
arrdc1a,
mpz,
vars,
ptgs2a,
dmrt2a,
ptch2,
egr2b,
tnw,
jak2b,
pou3f2b,
ta,
csnk2b,
rxrga,
rxrbb,
rxrba,
psmb9a,
vegfaa,
notch1a,
ctsla,
hiat1a,
glipr2,
prpf4,
uck2b,
brd3b,
vcp,
smarca2,
plk3,
ivns1abpb,
anxa1a,
sh3glb1b,
atp6v1g1,
sox4a,
tubb5,
nelfb,
klhl20,
amy2a,
aqp3a,
coq3,
sdhc,
pmpca,
daxx,
flot1a,
prkacbb,
ntrk2b,
gas1b,
ccbl1,
rxrab
|
| 16109975 |
The zebrafish gene map defines ancestral vertebrate chromosomes. Genome Res. Ian G Woods , Catherine Wilson , Brian Friedlander , Patricia Chang , Daengnoy K Reyes , Rebecca Nix , Peter D Kelly , Felicia Chu , John H Postlethwait , William S Talbot |
2005-09-01 |
fgfr4,
pik3r3b,
trpv6,
poldip2,
dnase2,
rtf1,
ube2g1b,
ppp1r14bb,
pvalb3,
znf207b,
olig1,
sufu,
msi2a,
ppp4ca,
ppp1cb,
socs9,
nhp2,
kat8,
laptm4a,
fsta,
mthfd2,
mob1a,
dyrk1aa,
greb1l,
fn1a,
aldh9a1a.1,
cpt2,
sh3gl1a,
vps18,
arrdc1a,
sv2bb,
idh1,
sb:cb37,
tle3b,
erbb4a,
ap1g2,
parp2,
hbl3,
dhx37,
pcsk7,
rmdn3,
gtf3ab,
kif3b,
npl,
sall1b,
pard6ga,
arfgef1,
gdf5,
cog1,
casr,
slc25a28,
urb1,
ndufv3,
trip11,
casq2,
mpz,
rps9,
vars,
spry4,
ube2ia,
dlg1,
sim2,
blzf1,
copb2,
sec22ba,
tnfsf10l,
ednraa,
pklr,
vcana,
ywhag1,
jag1a,
jag2b,
jag1b,
vim,
tfap2a,
prps1a,
atic,
cyp1a,
ckbb,
psap,
gbx1,
ptk2ab,
meis1b,
mkrn2,
rbp5,
crabp2a,
ccna2,
hdac1,
csnk1a1,
mak16,
actl6a,
dtl,
stil,
pole2,
slc25a5,
cct7,
cct3,
smc4,
kif11
|
| 12477932 |
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team |
2002-12-24 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
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|---|---|---|
| {{authorIndex+1}} |
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