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11438 Chrna4

11438

Chrna4

cholinergic receptor, nicotinic, alpha polypeptide 4

protein-coding

Mus musculus

基因描述

Type Description
Definition cholinergic receptor, nicotinic, alpha polypeptide 4

研究结论

Date Results Publications
2021-04-03 13:28:00 alpha4beta2 nicotinic acetylcholine receptors intrinsically influence body weight in mice. 31881170
2020-06-20 11:10:00 Following alpha4beta2 nAChR stimulation, activated translocated to the plasma membrane to induce clathrin-mediated endocytosis of D3R, resulting in downregulation and signal inhibition. 31078264
2019-09-07 11:43:00 Serine residues S336, S470 and S530 in Chrna4 protein have a brain region dependent modulatory role on surface alpha4beta2 nicotinic receptor expression. 30414940
2019-08-03 13:15:00 The numbers of nAChR alpha4 immuno-positive cells and western blot levels were significally increased by 15-Hz auricular electrical stimulation in the hippocampal CA2 output cortex. The numbers of choline acetyltransferase (ChAT) - a key enzyme for biosynthesis of ACh - immuno-positive cells and western blot levels had no significant differences. 31078140
2019-01-12 10:52:00 Acetylcholine tone fine-tunes the firing properties of Dopamine (DA) neurons of the ventral tegmental area through beta2-containing (beta2*) nicotinic Acetylcholine receptors. 30176987

名称对应

Type IDs
Synonymous Acra-4, Acra4, EBN1, ENFL1
Gene
UniProtKB-ID: ACHA4_MOUSE, Q53YK0_MOUSE
UniprotKB: O70174, Q53YK0
UniParc: UPI0000023D98
EMBL: AB010002, AK034228, AF225912, AK083157, AK143938, BC053013, AY574263, AK136886, AF325347
Ensembl: ENSMUSG00000027577
KO: mmu:11438
Nucleutide sequences
EMBL-CDS: AAL37363.1, AAF34716.2, BAC28638.1, AAH53013.1, BAA25752.1, BAC38788.1, BAE25619.1, AAS90359.1, BAE23155.1
Ensembl_TRS: ENSMUST00000067120
Protein sequencees
Ensembl_PRO: ENSMUSP00000066338
RefSeq: XP_006500614.1, XP_030102632.1, NP_056545.3
Others
UniRef100: UniRef100_O70174
UniRef90: UniRef90_P09483
UniRef50: UniRef50_P09483
UniGene: Mm.252369
CCDS: CCDS17192.1

全选

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