| Type | Description |
|---|---|
| Definition | cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle) |
| Date | Results | Publications |
|---|---|---|
| 2018-12-22 11:35:00 | A triad of residues aligning to Thr-152, Glu-209, and Lys-211 in Htr3, appear to be involved in side-chain interactions near binding sites in Htr3a (subunit alpha) and muscle-type Chrna1. Data suggest that mutating Htr3a triad to that of Chrna1 increases binding affinity of nicotine to Htr3a. (Htr3 = 5-hydroxytryptamine/serotonin receptor; Chrna1 = cholinergic receptor nicotinic alpha polypeptide 1) | 29298898 |
| 2017-09-09 11:44:00 | The results indicate that in the absence of the alpha1-nAChR subunit, clusters of nAChRs coupled to SK2 potassium channels as well as functional efferent synapses did form, showing that alpha1 is not necessary for these processes to take place. | 27098031 |
| 2016-12-17 10:51:00 | Findings suggest the possible role of controlling localised inflammatory response by parasympathetic cholinergic nerves through a1nAChRs of inflammation sites. | 26778394 |
| 2014-02-22 10:36:00 | This study demonstrates that genes coding for CHRNA1 subunits may contain variants associated with statin-induced ADRs. | 22688219 |
| 2012-12-08 11:28:00 | Chrna1 was co-purified with nicotinic acetylcholine receptor (AChR) in C2C12 myotubes. In addition, Stau1 was found to interact with Chrna1 mRNA, and knocking down of Stau1 by resulted in defective AChR clustering. | 22884571 |
| Type | IDs |
|---|---|
| Synonymous | AI385656, AI608266, Achr-1, Acra |
| Gene |
UniProtKB-ID:
ACHA_MOUSE,
Q05A24_MOUSE
UniprotKB:
P04756,
Q05A24
UniParc:
UPI0000003F8B
EMBL:
BC125439,
AK029177,
X03986,
BC137678,
M17640
Ensembl:
ENSMUSG00000027107
KO:
mmu:11435
|
| Nucleutide sequences |
EMBL-CDS:
AAB53942.1,
BAC26337.1,
CAA27624.1,
AAI25440.1,
AAI37679.1
Ensembl_TRS:
ENSMUST00000028515
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000028515
RefSeq:
NP_031415.2
|
| Others |
UniRef100:
UniRef100_P04756
UniRef90:
UniRef90_P04756
UniRef50:
UniRef50_P02708
UniGene:
Mm.4583
CCDS:
CCDS16132.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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