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11432 Acp2

11432

Acp2

acid phosphatase 2, lysosomal

protein-coding

Mus musculus

基因描述

Type Description
Definition acid phosphatase 2, lysosomal

研究结论

Date Results Publications
2015-01-03 10:51:00 ACP2 has critical roles in the development of the anterior cerebellum and it may regulate anterior and central zone compartmentation. 24722417
2014-05-31 11:53:00 These data suggest that ACP2 expression is dynamically regulated during development, and in the adult, it may function within a complex architecture that is linked to cerebellar modular organization. 23780826
2012-03-31 11:48:00 dephosphorylation of Man6P-containing lysosomal proteins requires the concerted action of Acp2 and Acp5 and is needed for hydrolysis and removal of degradation products 22158965
2010-01-21 00:00:00 Acp2 is the gene mutated in nax mice provides a valuable model system for studying the role of Acp2 in cerebellum and skin homeostasis. 15503243
2010-01-21 00:00:00 The data suggest that lysosomal dysfunction and accumulation of storage material require increased biogenesis of LAP/ACP2 and LAMP-2 positive membranes which makes LAP/ACP2 suitable as biomarker of Batten disease. 17868323

名称对应

Type IDs
Synonymous Acp-2, LAP
Gene
UniProtKB-ID: PPAL_MOUSE, Q3UZN1_MOUSE
UniprotKB: P24638, Q3UZN1
UniParc: UPI00000292B3, UPI00005AB9E8
EMBL: BC023343, AK133756, X57199
Ensembl: ENSMUSG00000002103
KO: mmu:11432
Nucleutide sequences
EMBL-CDS: CAA40485.1, AAH23343.1, BAE21825.1
Ensembl_TRS: ENSMUST00000002172, ENSMUST00000239169
Protein sequencees
Ensembl_PRO: ENSMUSP00000002172, ENSMUSP00000159053
RefSeq: XP_011237559.1, NP_031413.1, NP_001343996.1
Others
UniRef100: UniRef100_Q3UZN1, UniRef100_P24638
UniRef90: UniRef90_P20611
UniRef50: UniRef50_P20611
UniGene: Mm.45570
CCDS: CCDS16427.1

全选

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研究热度

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