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1143 CHRNB4

1143

CHRNB4

cholinergic receptor nicotinic beta 4 subunit

protein-coding

Homo sapiens

基因描述

Type Description
Definition cholinergic receptor nicotinic beta 4 subunit

研究结论

Date Results Publications
2021-02-27 13:52:00 The relationship between CHRNA5/A3/B4 gene cluster polymorphisms and lung cancer risk: An updated meta-analysis and systematic review. 33578531
2019-03-16 11:05:00 Results indicate rs4887074 is associated with nicotinic receptor CHRNB4 expression, and along with two regulatory variants of nicotinic receptors CHRNA3 and CHRNA5, modulates the effect of rs16969968 on nicotine dependence risk. 30453884
2019-02-16 10:18:00 We discovered a genome-wide significant interaction of the marker rs12440014 within the gene CHRNB4. The well-established association of the genomic region 15q25 to lung cancer might be influenced by exposure to radon among uranium miners. 29971594
2018-01-13 12:40:00 our results show that a genomic region with functionally related genes, such as the CHRNA5/CHRNA3/CHRNB4 cluster, is under coordinated regulatory control. 27758088
2017-09-09 10:45:00 The results of this study suggests a pleiotropic role of Chr15q25 CHRNA5-CHRNA3-CHRNB4 gene cluster with complex influences in ADHD, tobacco smoking and cognitive performance. 27302872

名称对应

Type IDs
Gene
UniProtKB-ID: ACHB4_HUMAN
UniprotKB: P30926
UniParc: UPI0001AE68DC, UPI0000125276
EMBL: AC067863, AC022748, BC096082, AF306325, AJ306458, AJ306457, AF306329, AJ306456, AF453877, AJ306459, BC096080, X68275, U48861, BC096083, BC096081, AF306328, AF306327, Y08416, AF306326, AJ306455, U62439, AJ306454
Ensembl: ENSG00000117971
KO: hsa:1143
Nucleutide sequences
EMBL-CDS: AAL02062.1, AAB40117.1, CAC34819.1, CAA69693.1, AAA92123.1, CAA48336.1, AAH96082.1, AAL57840.1, AAH96080.1, AAH96081.1, AAH96083.1
Ensembl_TRS: ENST00000412074, ENST00000261751
Protein sequencees
Ensembl_PRO: ENSP00000416386, ENSP00000261751
RefSeq: XP_011519493.1, XP_011519492.1, XP_011519494.1, NP_001243496.1, XP_016877376.1, XP_011519489.1, XP_016877378.1, XP_016877377.1, XP_016877374.1, XP_016877375.1, XP_011519488.1, NP_000741.1
Others
UniRef100: UniRef100_P30926
UniRef90: UniRef90_P30926
UniRef50: UniRef50_P30926
UniGene: Hs.624178
CCDS: CCDS10306.1, CCDS58392.1

全选

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