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114294 LACTB

114294

LACTB

lactamase beta

protein-coding

Homo sapiens

基因描述

Type Description
Definition lactamase beta

研究结论

Date Results Publications
2019-04-27 10:43:00 LACTB was downexpressed in gliomas. Downregulation of LACTB predicted poor survival of glioma and promoted cell proliferation, invasion, and angiogenesis of gliomas 28835318
2019-03-02 10:17:00 our findings successfully demonstrate for the first time that LACTB is a novel epigenetic silenced tumor suppressor through modulating the stability of p53, supporting the pursuit of LACTB as a potential therapeutic target for colorectal cancer 29899406
2017-08-12 10:25:00 observations uncover a novel mitochondrial tumour suppressor, LACTB--and demonstrate a connection between mitochondrial lipid metabolism and the differentiation program of breast cancer cells, thereby revealing a previously undescribed mechanism of tumour suppression 28329758
2016-06-04 10:48:00 MiR-125b-5p attenuates the secretion of MCP-1 by directly targeting inhibiting LACTB in LPS-stimulated THP-1 macrophages. 26603571
2010-12-05 22:09:00 Observational study of gene-disease association. (HuGE Navigator) 20877624

名称对应

Type IDs
Synonymous G24, MRPL56
Gene
UniProtKB-ID: LACTB_HUMAN
UniprotKB: P83111
UniParc: UPI0000160B85, UPI000013D220
EMBL: AK027808, BC067288, AY358709
Ensembl: ENSG00000103642
KO: hsa:114294
Nucleutide sequences
EMBL-CDS: BAB55384.1, AAQ89072.1, AAH67288.1
Gene_ORFName: UNQ843/PRO1781
Ensembl_TRS: ENST00000261893, ENST00000413507
Protein sequencees
Ensembl_PRO: ENSP00000261893, ENSP00000392956
RefSeq: NP_001275514.1, NP_116246.2, NP_741982.1
Others
UniRef100: UniRef100_P83111
UniRef90: UniRef90_P83111
UniRef50: UniRef50_P83111
UniGene: Hs.410388
CCDS: CCDS45275.1, CCDS10182.1

全选

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研究热度

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