| Type | Description |
|---|---|
| Definition | aconitase 1 |
| Date | Results | Publications |
|---|---|---|
| 2017-10-07 11:09:00 | IL-6 likely up-regulates IRP1 and DMT1 expression and down-regulates FPN1 expression in BV2 microglial cells through JNK signaling pathways | 28672025 |
| 2017-03-18 13:19:00 | Using whole RNA sequencing of bone marrow cells in iron-overloaded mice, it was observed that Idh1 and Aco1, enzymes involved in the TCA cycle, were elevated. | 27380194 |
| 2016-08-27 10:06:00 | The Irp1-/- mice develop polycythemia and pulmonary hypertension, and suggesting that Irp1 plays an essential role in erythropoiesis and in the pulmonary and cardiovascular systems. | 25771171 |
| 2016-05-07 11:08:00 | IRP1 and IRP2 mutant mice rapidly succumb to systemic infection with Salmonella Typhimurium, a pathogenic bacterium that multiplies within macrophages, with increased bacterial burdens in liver and spleen. | 26190773 |
| 2016-04-28 17:55:00 | results uncover an unexpected protective role of IRP1 in pathological conditions associated with altered Fe-S metabolism | 25651183 |
| Type | IDs |
|---|---|
| Synonymous | Aco-1, Irebp, Irp1 |
| Gene |
UniProtKB-ID:
ACOC_MOUSE
UniprotKB:
P28271
UniParc:
UPI00001C2EF3
EMBL:
AL831793,
X61147,
BC005454,
CH466538,
AK163985
Ensembl:
ENSMUSG00000028405
KO:
mmu:11428
|
| Nucleutide sequences |
EMBL-CDS:
AAH05454.1,
CAA43455.1,
EDL05446.1,
BAE37570.1
Ensembl_TRS:
ENSMUST00000102973
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000100038
RefSeq:
NP_031412.2,
XP_036019494.1
|
| Others |
UniRef100:
UniRef100_P28271
UniRef90:
UniRef90_P21399
UniRef50:
UniRef50_P21399
UniGene:
Mm.331547
CCDS:
CCDS18042.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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